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Figure 3 | Retrovirology

Figure 3

From: Single amino acid substitution (G42E) in the receptor binding domain of mouse mammary tumour virus envelope protein facilitates infection of non-murine cells in a transferrin receptor 1-independent manner

Figure 3

Virus replicating in human cells carries a human APOBEC3G signature of cytosine deamination. Nucleotide sequences obtained as described in Figure 3 were examined for the presence of hAPOBEC3G-mediated nucleotide changes on minus sense DNA. (A) All possible nucleotide transversions and transitions detected in the pro (a portion), pol, env and sag genes are expressed as a percentage of total number of nucleotide substitutions. (B) All C-to-T mutations found in the minus sense DNA strand were analysed for sequence context at the −1 and −2 nucleotide position.

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Retrovirology

ISSN: 1742-4690

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