From: Key determinants of target DNA recognition by retroviral intasomes
Library | Unique sites | Within Refseq genes (%) | Within 5 kb (+/− 2.5 kb) of CpG (%) | Within 5 kb (+/− 2.5 kb) of TSS (%) | Average gene density per Mb (+/− 0.5 Mb) of integration sites |
---|---|---|---|---|---|
PFV | 2,924 | 1,180 (40.4) | 450 (15.4) | 425 (14.5) | 10.8 |
PFV (in vitro) | 22,117 | 10,506 (47.5) | 1,349 (6.1) | 1,150 (5.2) | 10.3 |
MoMLV | 53,463 | 30,865 (57.7) | 15,157 (28.4) | 14,870 (27.8) | 15.4 |
PERV | 1,668 | 936 (56.1) | 811 (48.6) | 676 (40.5) | 23.4 |
XMRV | 5,487 | 3,086 (56.2) | 1,022 (18.6) | 1,100 (20.1) | 14.5 |
EIAV | 1,172 | 689 (58.8) | 70 (6.0) | 69 (5.9) | 12.1 |
HIV-1 | 335,968 | 250,552 (74.6) | 18,871 (5.6) | 13,882 (4.1) | 19.9 |
Rev-A | 834 | 460 (55.2) | 216 (25.9) | 216 (25.9) | 15.7 |
SIV | 168 | 142 (84.5) | 4 (2.4) | 3 (1.8) | 17.8 |
ASLV | 916 | 320 (54.7) | 55 (9.4) | 44 (7.5) | 11.3 |
HERV-K | 1,071 | 541 (50.5) | 131 (12.2) | 108 (10.1) | 17.8 |
HTLV-1 | 6,820 | 3148 (49.8) | 523 (8.3) | 467 (7.4) | 10.7 |
MMTV | 178,574 | 72,035 (40.3) | 7,131 (4.0) | 6,957 (3.9) | 8.3 |
MRC | 282,824 | 129,287 (45.7) | 12,914 (4.6) | 13,942 (4.9) | 9.2 |