Figure 1
From: Jaagsiekte sheep retrovirus infection of lung slice cultures
Viability and structure of cultured ovine lung slices. Hematoxylin and eosin (HE) stained uninfected lung slices at 0 (A), 16 (B) and 42 (C) dpi. In panel B the arrows indicate areas of “thickening” around the edges of the lung slice. In panel C the small arrow indicates epithelial cells and the large arrow indicates necrotic interstitial cells. D, E, F) IHC of d16 lung slices labeled with anti-Ki-67 (D), anti-pan-cytokeratin (E), and anti-DC-LAMP (F). Lung slices D, E and F were treated with the replication-defective JSRV-∆RT virus.