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Table 2 Differential HERV-K (HML-2) transcription in the uninfected and persistently infected human T-lymphoma cell line KE37.1

From: Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection

Provirus a

Chromosome band

Location of amplicon in genome b

Number of clones (% cloning frequency)

   

KE37.1

KE37.1-IIIB c

ERVK-1d,e (c1_A, K116, K4)

1p31.1

75617005–75617599

1 (2.9)

-

ERVK-7d (c1_B, K102, K50a)

1q22

153870019–153870613

18 (51.4)

40 (87.0)

ERVK-18 (c1_C, K110, K18)

1q23.3

158928865–158929429

7 (20.0)

-

ERVK-3d,e (c3_B, K106, K68)

3q13.2

114232739–114233333

1 (2.9)

1 (2.2)

ERVK-4d (c3_C, K (I))

3q21.2

127093473–127094067

-

-

ERVK-12 (c4_A, K5)

4q32.2

161800867–161801461

1 (2.9)

-

ERVK-10d (K107, K10, c5)

5q33.3

156024233–156024827

1 (2.9)

1 (2.2)

ERVK-9e (c6_A, K109, envK4)

6q14.1

78490569–78491163

-

1 (2.2)

ERVK-15 (c7_C, K (OLDAC004979))

7q34

141101012–141101702

6 (17.1)

2 (4.3)

ERVK-28

19q12

32827928–32828522

-

1 (2.2)

Total number of clones

35 (100%)

46 (100%)

  1. aDesignation according to [87], aliases are in parentheses.
  2. bAccording to the March 2006 assembly (NCBI36/hg18) of the human genome sequence at the Human Genome Browser [88].
  3. chuman T-lymphoma cell line KE37.1 persistently infected with HIV-1IIIB/LAI.
  4. dHuman-specific HERV-K (HML-2) proviruses [89].
  5. ePolymorphic in the human genome [89].
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Retrovirology

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