Skip to main content

Table 1 Differential HERV-K (HML-2) transcription in de novo and persistently infected LC5 cells

From: Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection

Provirus a

Chromosome band

Location of amplicon in genome b

Number of clones (% cloning frequency)

   

LC5-RIC

LC5-RIC-HIV c

LC5

LC5-HIV d

ERVK-7e (c1_B, K102, K50a)

1q22

153870020–153870613

-

2 (7.1)

-

-

ERVK-18 (c1_C, K110, K18)

1q23.3

158928993–158929564

1 (2.1)

-

-

-

ERVK-3e,f (c3_B, K106, K68)

3q13.2

114232740–114233333

-

2 (7.1)

2 (2.2)

-

ERVK-4e (c3_C, K (I))

3q21.2

127093474–127094067

1 (2.1)

1 (3.6)

2 (2.2)

-

ERVK-6e,f (c7_A, K (HML-2. HOM), K108)

7p22.1

4604296–4604932

-

-

-

44 (47.3)

4595814–4596407g

    

ERVK-14e (c7_B)

7q22.1

104179245–104179826

1 (2.1)

-

-

-

ERVK-15 (c7_C, K (OLDAC004979))

7q34

141101009–141101702

-

21 (75.0)

1 (1.1)

-

ERVK-17e (c10_B)

10q24.2

101576433–101577026

-

2 (7.1)

-

-

ERVK-25e,f (c11_A, K36, K118)

11q22.1

101072651–101073244

3 (6.4)

-

-

-

ERVK-20 (c11_B, K37)

11q23.3

118103858–118104446

40 (85.1)

-

84 (94.4)

49 (52.7)

ERVK-21 (K (C12), K41, K119)

12q14.1

58728458–58729051

1 (2.1)

-

-

-

Total number of clones

47 (100)

28 (100)

89 (100)

93 (100)

  1. aDesignation according to [87], aliases are in parentheses.
  2. bAccording to the March 2006 assembly (NCBI36/hg18) of the human genome sequence at the Human Genome Browser [88].
  3. c de novo infected LC5-RIC cells.
  4. dpersistently infected LC5 cells.
  5. eHuman-specific HERV-K (HML-2) proviruses [89].
  6. fPolymorphic in the human genome [89].
  7. gThe human reference genome sequence harbors a tandem provirus [90]. Due to the lack of sufficient sequence differences the detected cDNA sequence may stem from one or the other provirus.
Back to article page

Retrovirology

ISSN: 1742-4690

Contact us