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Table 3 HLA-RM9 contact table

From: A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

 

B0702

B8101

B4201

B4202

TL9

VdW

HB/SB

VdW

HB/SB

VdW

HB/SB

VdW

HB/SB

Arg1

37

5

35

4

30

4

30

4

Pro2

23

0

22

0

26

0

21

1

Gln3

27

1

23

2

24

2

26

2

Val4

2

0

2

0

2

0

2

0

Pro5

12

0

10

1

8

0

9

0

Leu6

17

0

6

0

4

0

10

0

Arg7

17

4

4

0

11

0

11

0

Pro8

9

1

9

0

15

1

14

1

Leu9

31

5

30

5

56

10

30

4

Total

175

16

141

12

176

17

153

12

BSA (Å)

1813.8

 

1843.4

 

1720.2

 

1796

 

SC (Å)

0.757

 

0.751

 

0.797

 

0.807

 
  1. HB = hydrogen bond, SB = salt bridge, vdW = van der Waals interactions, BSA = buried surface area, SC = surface complementarity.
  2. *A 3.4 Å cut-off was used for HBs and SBs, and a 4 Å cut-off was used for vdW.