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Figure 4 | Retrovirology

Figure 4

From: Intasome architecture and chromatin density modulate retroviral integration into nucleosome

Figure 4

Comparison of HIV-1, PFV, MLV and ASV integration sites and nucleosome occupanc in vitro . Fifty PFV (A), HIV-1 (B), MLV (C) and ASV (D) integrants carrying the correct target DNA duplication obtained after integration assay carried on the p5S vector chromatinized with a 1/1.3 DNA/histones ratio and localized in the 5S-G5E4 fragment were positioned onto the DNA sequence and compared to the nucleosome occupancy determined using the method previously described by [53] and used in [36].

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