Table 1 Raw densities of the transcription factors included in the Protein/DNA array analysis, grouped according to association with general signaling pathways
| Â | Â | Raw densities | |||
|---|---|---|---|---|---|
Signaling pathways | Transcription factors | Jurkat | MT-2 | Control CD4 | Infected CD4 T cells |
Akt signaling | AP-(2) | 29011 ± 312 | 36283 ± 2049 | 126 ± 3 | 285 ± 2 |
Brn-3 | 20098 ± 857 | 43533 ± 350 | 0 | 262 ± 2 | |
GATA | 12325 ± 357 | 34756 ± 1662 | 0 | 284 ± 1 | |
NFAT | 16264 ± 921 | 35151 ± 358 | 103 ± 2 | 284 ± 1 | |
NF-E1 | 27661 ± 910 | 45077 ± 611 | 120 ± 1 | 326 ± 3 | |
PAX-5 | 26980 ± 1038 | 33945 ± 97 | 120 ± 1 | 261 ± 2 | |
Pit-1 | 11622 ± 386 | 29345 ± 283 | 0 | 296 ± 3 | |
PPAR | 13329 ± 467 | 31100 ± 82 | 107 ± 2 | 264 ± 1 | |
PRE | 14780 ± 196 | 30151 ± 417 | 109 ± 0 | 263 ± 3 | |
TR | 23845 ± 973 | 3172 ± 231 | 0 | 296 ± 3 | |
MAP kinase signaling | AP-1(2) | 26548 ± 1383 | 39830 ± 2086 | 133 ± 8 | 284 ± 1 |
AP-1(1) | 19105 ± 524 | 45066 ± 1252 | 100 ± 1 | 284 ± 1.6 | |
CDP | 14854 ± 434 | 29735 ± 75 | 106 ± 2 | 253 ± 2 | |
CEBP | 20286 ± 68 | 37664 ± 693 | 115 ± 3 | 257 ± 2 | |
E2F1 | 25614 ± 251 | 47332 ± 149 | 126 ± 6 | 323 ± 8 | |
ER | 30792 ± 1518 | 42869 ± 335 | 127 ± 7 | 284 ± 4 | |
Ets | 17337 ± 489 | 32485 ± 1058 | 114 ± 1 | 265 ± 3 | |
IRF-1 | 13996 ± 124 | 26838 ± 30 | 102 ± 1 | 241 ± 2 | |
MEF-1(1) | 23260 ± 405 | 47037 ± 954 | 133 ± 1 | 287 ± 2 | |
MEF-2(1) | 15230 ± 107 | 28955 ± 492 | 105 ± 2 | 244 ± 5 | |
c-Myb | 23884 ± 1150 | 32938 ± 656 | 118 ± 0 | 270 ± 2 | |
NF-1 | 14970 ± 920 | 28197 ± 45 | 114 ± 1 | 258 ± 5 | |
Pbx-1 | 13464 ± 336 | 29920 ± 67 | 109 ± 0 | 245 ± 4 | |
p53 | 24993 ± 372 | 31927 ± 89 | 120 ± 0 | 270 ± 2 | |
USF-1 | 277010 ± 272 | 34861 ± 171 | 117 ± 2 | 285 ± 0 | |
VDR/DR-3 | 26164 ± 145 | 32870 ± 246 | 117 ± 0 | 281 ± 1 | |
NF-kB signaling | HSE | 15326 ± 371 | 30604 ± 440 | 111 ± 0 | 263 ± 5 |
NF-E2 | 28464 ± 800 | 39988 ± 2116 | 117 ± 2 | 307 ± 4 | |
JAK/STAT signaling | GAS/ISRE | 12857 ± 427 | 34972 ± 566 | 109 ± 4 | 238 ± 10 |
HNF-4 | 19187 ± 108 | 42759 ± 1490 | 116 ± 1 | 281 ± 1 | |
STAT 1 | 15351 ± 156 | 32659 ± 157 | 116 ± 1 | 294 ± 5 | |
STAT 3 | 17637 ± 567 | 33608 ± 142 | 116 ± 2 | 0 | |
STAT 4 | 29321 ± 608 | 37269 ± 462 | 126 ± 2 | 270 ± 0 | |
TGF-β signaling | FAST-1 | 15054 ± 756 | 33012 ± 477 | 116 ± 0 | 294 ± 5 |
Myc/Max | 26136 ± 1301 | 0 | 0 | 0 | |
RAR/DR-5 | 28178 ± 45 | 36611 ± 97 | 117 ± 0 | 275 ± 2 | |
SBE/Smad | 16635 ± 511 | 30441 ± 626 | 108 ± 1 | 248 ± 5 | |