Figure 1

Viral loads in FV-infected TLR3 ^−/−and TLR7 ^−/−mice. TLR3^+/+ and TLR3^−/− mice were infected with 20,000 SFFU of FV and viral loads in the spleen were determined by infectious center assay at days 4 (A) and 10 (B) post infection. In addition, plasma viral loads from FV-infected TLR7^−/− and TLR7^+/+ mice at 7 dpi were measured by qPCR (C). At least five mice per group were analyzed. Individual percentages and mean values are indicated by bars and dots + SEM. Statistically significant differences between FV-infected TLR3^+/+ and TLR3^−/− mice are indicated by * for p < 0.05.