Reagent for IgA isolation | IgA site recognized | IgA form recognized | References |
---|---|---|---|
Jacalin resin | α-D-galactose (O-linked) in the IgA1 hinge | Preferential binding to all IgA1 forms; Weak binding to IgA2 | |
Staphylococcal superantigen-like protein 7 | Fc | Specific for all IgA1 and IgA2 forms | |
Streptococcal IgA-binding peptide | Fc | Specific for all IgA1 and IgA2 forms | |
mAbs | Â | Â | Â |
Anti-J chain mAb | J chain | Specific for dimeric and secretory forms of IgA1 and IgA2 | Commercially available |
Anti-SC mAb | SC | Specific for secretory forms of IgA1 and IgA2 | |
Specific anti-IgA1 mAb | Constant region | Specific for IgA1 | |
Specific anti-IgA2 mAb | Constant region | Specific for IgA2 |