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Table 2 Human IgA isolation methods

From: Are anti-HIV IgAs good guys or bad guys?

Reagent for IgA isolation IgA site recognized IgA form recognized References
Jacalin resin α-D-galactose (O-linked) in the IgA1 hinge Preferential binding to all IgA1 forms; Weak binding to IgA2 [33],[34],[37]
Staphylococcal superantigen-like protein 7 Fc Specific for all IgA1 and IgA2 forms [36],[39]
Streptococcal IgA-binding peptide Fc Specific for all IgA1 and IgA2 forms [35],[38]
mAbs    
Anti-J chain mAb J chain Specific for dimeric and secretory forms of IgA1 and IgA2 Commercially available
Anti-SC mAb SC Specific for secretory forms of IgA1 and IgA2
Specific anti-IgA1 mAb Constant region Specific for IgA1
Specific anti-IgA2 mAb Constant region Specific for IgA2