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Table 1 Green fluorescence protein (GFP) expression on GHOST cell lines exposed to different HIV isolates

From: HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage

Viruses

GFP expression in GHOST cells*

GHOST-CD4/CCR5

GHOST-CD4/CXCR4

GHOST-CD4/CCR8

GHOST-CD4/Hi5

GHOST-CD4/CX3CR1

GHOST-CD4

HIV-2MIC97

-

-

+

-

-

-

HIV-2MJC97

-

-

+

-

-

-

HIV-2ROD

+

+

-

+

-

-

HIV-1Ba-L

+

-

-

+

-

-

Mock infected

-

-

-

-

-

-

  1. GHOST cells express either CD4 alone (GHOST-CD4) or CD4 together with different coreceptors.
  2. *LTR-driven GFP expression was analized in GHOST cells by fluorescent microscopy at days 1, 3, 6, 9 and 12 days after infection; + presence of GFP-expressing cells; − absence of GFP-expressing cells.