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Figure 1 | Retrovirology

Figure 1

From: Emergence of CD134 cysteine-rich domain 2 (CRD2)-independent strains of feline immunodeficiency virus (FIV) is associated with disease progression in naturally infected cats

Figure 1

Representative example of results obtained from receptor utilisation assay testing six autologous Env variants isolated from cat M31 and two reference Envs, GL8 (CRD2-dependent) and B2542 (CRD2-independent). The mean luciferase counts per minute (cpm) for each cell line with standard errors (n = 3) are presented for MCC cells [35] expressing the entire human CD134 molecule (HHH, open bars), cells expressing the human x feline CD134 containing the human CRD2 domain (FFHH, hatched bars) and cells expressing the entire feline CD134 molecule (FFF and CLL-CD134 cells [29], shown in chequered and grey bars respectively). Note the differences in titres on cells expressing the human x feline CD134 chimaera containing the human CRD2 domain (FFHH cells, hatched bars) and subsequent pseudotype classification as CRD2-dependent or –independent.

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Retrovirology

ISSN: 1742-4690

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