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Figure 5 | Retrovirology

Figure 5

From: Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein

Figure 5

Triptolide specifically reduces steady-state level of Tat protein. (A) HeLa cells were transfected with pEF1-FLAG-Tat in the presence of increasing concentrations of triptolide. Cells were harvested 48 h post-transfection, and protein expression levels were determined by Western blotting. (B) HeLa cells were transfected either with pEF1-GFP (left) or pEF1-Tat-GFP (right) in the presence of increasing concentrations of triptolide. Cells were harvested 48 h post-transfection, and protein expression levels were determined by Western blotting.

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