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Table 3 Thermal denaturation of N and C peptide mixtures modeling the 6HB

From: Resistance to N-peptide fusion inhibitors correlates with thermodynamic stability of the gp41 six-helix bundle but not HIV entry kinetics

Env construct

Tm(°C)a

WT-WT

43.5

C1-C1

53.1

C2-C2

57.5

C3-C3

49.0

C4-C4

54.0

C5-C5

49.0

C6-C6

65.0

WT-E560K

49.0

WT-KKR

54.1

  1. aall but C1-C1 and WT-KKR were determined previously.
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Retrovirology

ISSN: 1742-4690

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