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Figure 2 | Retrovirology

Figure 2

From: Resistance to N-peptide fusion inhibitors correlates with thermodynamic stability of the gp41 six-helix bundle but not HIV entry kinetics

Figure 2

6HB thermostablity increases with N-peptide resistance. Scatter plots show correlation between transition mid-point temperature (Tm) and peptide resistance of pseudoviruses relative to wild type (WT) for (A) N44, (B) N36, and (C) IZN36. Each dot in (A) represents the mean resistance for each Env depicted in Figure 1B and C. Results in (B-C) were derived from Envs reported previously. Linear regressions and statistics for correlation are indicated for each panel. rs, Spearman correlation coefficient.

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Retrovirology

ISSN: 1742-4690

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