Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART

Retrovirology

Table 4 Regression analysis of B cell phenotypical changes in relation to age and treatment duration

B cell phenotype	Variables included in the model			R²	P value
B cell phenotype	Age	Treatment duration	Interaction	R²	P value
AM_PD1				0.033	0.258
RM_PD1				0.016	0.438
naïve_PD1				0.002	0.771
TLM_PD1				0.003	0.737
AM_FcRL4			+	0.109	0.035
RM_FcRL4				0.020	0.372
naïve_FcRL4				0.015	0.452
TLM_FcRL4		+		0.135	0.018
AM_CD25		+		0.127	0.022
RM_CD25		+		0.172	0.007
naïve_CD25				0.045	0.185
TLM_CD25				0.017	0.423
AM_CD69				0.018	0.403
RM_CD69				0.030	0.276
naïve_CD69				0.016	0.431
TLM_CD69				0.010	0.533

Each row represents the regression result for one B cell subpopulation. For each population, the variables that were found predictive are marked with a "+". R² is the correlation coefficient between the specific B cell subpopulation and the chosen predictive variable(s). P values in bold indicate significant difference.

ISSN: 1742-4690