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Figure 7 | Retrovirology

Figure 7

From: Partial rescue of V1V2 mutant infectivity by HIV-1 cell-cell transmission supports the domain’s exceptional capacity for sequence variation

Figure 7

The effect of residue N160 on free virus infection and cell-cell transmission. Eight viruses encoding N160 and 3 viruses encoding K160 were probed as wt and upon N160K or K160N mutation in free virus infection (black) and cell-cell transmission (red). Mutant env infectivity in the two transmission pathways is normalized to the matching wt env. Values of relative efficacy of each mutant in cell-cell transmission over free virus infection are indicated below the bars; stars depict whether this difference reached statistical significance as probed by multiple unpaired t-tests with alpha = 0.05. Data shown are means and SD from 2 to 3 independent experiments performed in duplicates.

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Retrovirology

ISSN: 1742-4690

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