Table 1 Oligonucleotides used in this study

X01f

5′-CACACAGCTAGCATCATGGGACAGACCGTAACTACCCCTCTG-3′

X01r

5′-GCGAAGGCATAGCGGCTATCAGTGT-3′

X02f

5′-ATCCACTTCGAGGGATCAGGAGCTC-3′

X02r

5′-GCGAAGGCATAGCGGCTATCAGTGT-3′

X03f

5′-AACTGGGACCTTGGCGTCGGC-3′

X03r

5′-GTGTGTGCGGCCGCTCAGGGGGCCCCACGGGT-3′

M01f

5′-CACACAGCTAGCATGGGCCAGACTGTTACCACTCCC-3′

M01r

5′-CTGGGCGCTCGAGGGGAAAAG-3′

M02f

5′-CTTTTCCCCTCGAGCGCCCAG-3′

M02r

5′-CTTCGGCCAGGATATCAAGGCAGTTG-3′

M03f

5′-CAACTGCCTTGATATCCTGGCCGAAG-3′

M03r

5′-GTGTGTGCGGCCGCTTAGGGGGCCCCACGGGTTAATC-3′

M04f

5′-CACACAGCGGCCGCCTGCCAGTCCCCCTGG-3′

M04r

5′-GTGTGTCTCGAGGATATCAAGGCAGTTGTGTTGCAGCC-3′

M05f

5′-CACACACTCGAGCTGCCAGTCCCCCTGG-3′

M05r

5′-GTGTGTTCTAGAGATATCAAGGCAGTTGTGTTGCAGCC-3′

X04f

5′-CACACAGGTACCCTGCCAGTCCCCCTGG-3′

X04r

5′-GTGTGTGAATTCGCAGTCATGGGGGGCTTCCTTTTC-3′

X05f

5′-CACACAGCGGCCGCCTGCCAGTCCCCCTGG-3′

X05r

5′-GTGTGTCTCGAGGCAGTCATGGGGGGCTTCCTTTTC-3′

X06f

5′-CACACACTCGAGCTGCCAGTCCCCCTGG-3′

X06r

5′-GTGTGTTCTAGAGCAGTCATGGGGGGCTTCCTTTTC-3′

X07f

5′-CACACAGGTACCATCTTGGCTGAGACGCACGGAACC-3′

X07r

5′-GTGTGTGAATTCTCAGGGGGCCCCACGGGTTA-3′

X08f

5′-CACACAGGTACCCCACCCTGTTTGATGAGGCACTGC-3′

X09r

5′-GTGTGTGAATTCGTTTGACCAGTGCTTCTACCGCATGG-3′

X10r

5′-GTGTGTGAATTCAGGTAGGCCACAGGCCGACGC-3′

X11r

5′-GTGTGTGAATTCCTTGATAGGCCTTTTGCTGGTCTGGG-3′

X12r

5′-GTGTGTGAATTCGTCTTCGGAGTGGGCTGCCCC-3′

X13r

5′-GTGTGTGAATTCGGTTTGTAATAGGGCCCGAGTACCTCG-3′

X14f

5′-CACACAGCGGCCGCGGAGGTCAGGGTCAGGAGCCCC-3′

X14r

5′-GTGTGTCTCGAGGAATTCGGTACCAGTATTCCCTGGTCCAACAGCC-3′

X15r

5′-GTGTGTGCGGCCGCTCAGTCACCTAAGGTCAGGAGGGAGGTCTG-3′

T01f

5′-CACACATCTAGAGCCACCATGGCGGACGAGGGGAAGTCG-3′

T01r

5′-GTGTGTGCGGCCGCTCACTTCATGAATGCCACTTCTGGGATC-3′

T02f

5′-CACACAGCTAGCGCCACCATGAGAAAATACAGAAGCCACTGGTCTCAG-3′

T02r

5′-GTGTGTGCGGCCGCTTAACTACTAGACCAATCTTGAAAACGGAAGC-3′

T03f

5′-CACACAGCTAGCGCCACCATGCATCGTGATTCCTGTCCATTGG-3′

T03r

5′- GTGTGTGCGGCCGCCTATTTCCTTTCATTTGACCTAGATCGACTACG-3′

T04f

5′- CACACAGCTAGCGAAAAAAGAAGTAGAAATCGTGGCCCAC-3′

T05f

5′- GAACTGTCGAATGGTGAAAAAGAAAGTGAAAATGAAGGCCCACCTCCCT

CTTGGGG-3′

T05r

5′- CCCCAAGAGGGAGGTGGGCCTTCATTTTCACTTTCTTTTTCACCATTCGA

CAGTTC-3′

T06f

5′- CACACAGCTAGCGCCACCATGAGTGGCTGTCGGGTATTCATCG-3′

T06r

5′- GTGTGTGCGGCCGCTTAATTGCCACTGTCAACTGATCTGGACC-3′

X18f

5′-GTCAACAAGCGGGTGGATCGCGTCCACCCCACCGTGCC-3′

X18r

5′-GGCACGGTGGGGTGGACGCGATCCACCCGCTTGTTGAC-3′

X19f

5′-GTCACCTTCCTGGTAAACACTGGCGCCCAACACTCCGTG-3′

X19r

5′-CACGGAGTGTTGGGCGCCAGTGTTTACCAGGAAGGTGAC-3′

X20f

5′-CACACAGAATTCCCTGCCTTCGCCTCCCAGGTAAG-3′

X20r

5′-GTGTGTCTCGAGGGGGCCCCACGGGTTAATCTTATC-3′

X21f

5′-AGCTCACTTACACGCCCTCCAAGCAGT-3′

X21r

5′-ACTGCTTGGAGGGCGTGTAAGTGAGCT-3′

X22f

5′-CTTCGCCTCCCAGCTAAGTCAGTCAG-3′

X22r

5′-CTGACTGACTTAGCTGGGAGGCGAAG-3′

X26f

5′-CACACAGAATTCGGAAAGGACCCTACACCGTCCTGC-3′

X27f

5′-CACACAGAATTCCCCTCCAAGCAGTACAACAAGAGGTCTG-3′

Mir30f

5'-AAGGCTCGAGAAGGTATATTGCTGTTGACAGTGAG-3'

Mir30r

5'-AGCCCCTTGAATTCCGAGGCAGTAGGCA-3'

NXF1 - + KD

5'-TGCTGTTGACAGTGAGCGACGACGTGCTTTGCTGTATAAATAGTGAAGCCAC

AGATGTATTTATACAGCAAAGCACGTCGCTGCCTACTGCCTCGGA-3′

NXF1-2 KD

5′- TGCTGTTGACAGTGAGCGCACCCTGAGGATCATTGAAGAGTAGTGAAGCCA

CAGATGTACTCTTCAATGATCCTCAGGGTATGCCTACTGCCTCGGA-3';

NXF1-3

5'-TGCTGTTGACAGTGAGCGATGCCAGGAAGCCAAAGCTTACTAGTGAAGCCA

KD

CAGATGTAGTAAGCTTTGGCTTCCTGGCACTGCCTACTGCCTCGGA-3'

Codon optimized XMRV gag

5′-ATGGGCCAGACCGTGACCACCCCCCTGAGCCTGACCCTGCAGCATTGGGG

CGACGTGCAGCGGATCGCCAGCAACCAGAGCGTGGACGTGAAAAAGCGGAGATGGGTCACCTTCTGCAGCGCCGAGTGGCCCACCTTCAACGTGGGCTGGCCCCAGGACGGCACCTTCAATCTGGGCGTGATCAGCCAGGTCAAAAGCCGGGTGTTCTGCCCTGGCCCCCACGGACACCCTGACCAGGTGCCCTACATCGTGACCTGGGAGGCCCTGGCCTACGACCCTCCACCCTGGGTCAAGCCCTTCGTGTCCCCTAAGCCCCCACCCCTGCCTACAGCTCCAGTGCTGCCTCCTGGCCCTAGCGCCCAGCCTCCTAGCAGAAGCGCCCTGTACCCCGCCCTGACCCCATCCATCAAGAGCAAGCCCCCCAAGCCTCAGGTGCTGCCCGATTCTGGCGGCCCTCTGATCGACCTGCTGACCGAGGACCCCCCTCCATATGGCGCCCAGCCAAGCAGCAGCGCCAGAGAGAACAACGAGGAAGAGGCCGCCACCACCAGCGAGGTGTCCCCACCTAGCCCTATGGTGTCCCGGCTGCGGGGAAGAAGAGATCCTCCTGCCGCCGACAGCACCACCAGCCAGGCCTTCCCACTGAGAATGGGCGGCGACGGCCAGCTGCAGTACTGGCCTTTCAGCAGCAGCGACCTGTACAACTGGAAGAACAACAACCCCAGCTTCAGCGAGGACCCTGGCAAGCTGACCGCCCTGATCGAGAGCGTGCTGATCACCCACCAGCCCACCTGGGACGACTGCCAGCAGCTCCTGGGCACCCTGCTGACAGGCGAAGAGAAGCAGCGGGTGCTGCTGGAAGCCAGAAAGGCCGTGCGGGGCAACGACGGCAGACCTACCCAGCTGCCCAACGAAGTGAACGCCGCCTTCCCCCTGGAACGGCCCGACTGGGACTACACCACCACCGAGGGCCGGAACCACCTGGTGCTGTACAGACAGCTGCTGCTGGCTGGCCTGCAGAATGCCGGCAGAAGCCCCACCAACCTGGCCAAAGTGAAGGGCATCACCCAGGGCCCCAACGAGAGCCCCAGCGCCTTCCTGGAAAGACTGAAAGAGGCCTACCGGCGGTACACCCCCTACGATCCTGAGGACCCTGGCCAAGAAACAAACGTGTCCATGAGCTTCATCTGGCAGAGCGCCCCTGACATCGGCCGGAAGCTGGAACGGCTGGAAGATCTGAAGTCCAAGACCCTGGGGGACCTCGTGCGCGAGGCCGAGAAGATCTTCAACAAGAGAGAGACACCCGAGGAACGGGAAGAGAGAATCCGGCGCGAGATCGAGGAAAAAGAGGAACGGCGCAGAGCCGAGGACGAGCAGAGAGAGCGCGAGAGAGACAGACGGCGGCACAGAGAGATGAGCAAGCTGCTGGCCACCGTGGTCATCGGCCAGCGGCAGGATAGACAGGGCGGCGAGAGAAGAAGGCCCCAGCTGGACAAGGACCAGTGCGCCTACTGCAAAGAGAAGGGCCACTGGGCCAAGGACTGCCCCAAGAAGCCCAGAGGACCTAGGGGCCCTAGACCTCAGACCAGCCTGCTGACACTGGGCGATTGA-3′