Figure 6From: A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutantsNNRTI-binding pocket superposition of the crystal structures of K103N-Y181C mutant RT/21 (yellow protein and green ligand) and K103N/Y181C mutant RT/rilpivirine (PDB ID. 3BGR; blue protein and gray ligand). The hydrogen bonds are represented as dotted lines, and the most significant structural differences are indicated by red arrows.Back to article page