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Table 5 Inactivation of clinical isolates from different HIV-1 subtypes by WDO-217

From: A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

 

CCID50/ml

UG275

ETH2220

UG270

BZ163

BCF-Dioum

subtype A

subtype C

subtype D

subtype F

subtype G

untreated control

16242

64969

25781

16242

25781

WDO-217 (125 μM)

2558

2558

6446

2558

2558

  1. CCID 50 : 50% cell culture infectious dose as determined by titration on PBMCs.
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Retrovirology

ISSN: 1742-4690

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