Compound | EC50(μM) | CC50(μM) |
---|
HIV-1 IIIB | HIV-2 ROD | SIV Mac251 |
---|
WDO-217 | 7.9 ± 3.3 | 2.3 ± 0.3 | 5.3 ± 1.5 | 72 ± 11 |
AZT | 0.007 ± 0.001 | 0.005 ± 0.0008 | 0.016 ± 0.007 | >35 |
- Values are presented as mean ± std dev from at least 3 independent experiments.
- EC
50
: 50% effective concentration, concentration of inhibitor required for 50% inhibition of viral replication.
- CC
50
: 50% cytotoxic concentration, concentration of inhibitor that kills 50% of the cells.