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Table 3 Nucleotide composition of the different HIV-1 subtypes (group M)

From: The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus

Comparison P-valuea for A-content difference P-value for C-content difference P-value for G-content difference P-value for U-content difference
Subtype B/subtype Ab 0.0008 0.003 0.01 0.03
Subtype B/subtype C 0.0002 <0.0001 <0.0001 0.0004
Subtype A/subtype C 0.03 0.03 0.007 0.12
Subtype B/subtype D <0.0001 0.70 <0.0001 0.29
Subtype A/subtype D <0.0001 0.20 <0.0001 0.22
Subtype C/subtype D <0.0001 0.02 <0.0001 0.009
Subtype A/subtype G <0.0001 0.88 <0.0001 0.04
Subtype A/CRF02_AG 0.84 0.25 1.00 0.30
Subtype G/CRF02_AG <0.0001 0.45 <0.0001 0.004
  1. a Differences in nucleotide composition between HIV-1 subtypes were analysed using Student’s t-test.
  2. b Based on 41 subtype B, 62 subtype A, 55 subtype C, 38 subtype D, 18 subtype G and 32 recombinant CRF02_AG gag-pol-env sequences.