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Table 1 Average nucleotide composition of full-length lentivirus DNA genomes

From: The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus

Primate lentivirus

No. of genomes analysed

A (%) ± std

C (%) ± std

G (%) ± std

T (%) ± std

HIV-1, group M, subtype A

3

35.1 ± 0.2

18.1 ± 0.2

24.4 ± 0.3

22.4 ± 0.4

HIV-1, group M, subtype B

18

35.3 ± 0.2

18.1 ± 0.2

24.4 ± 0.2

22.3 ± 0.1

HIV-1, group M, subtype C

18

35.5 ± 0.2

18.0 ± 0.2

24.2 ± 0.1

22.3 ± 0.1

HIV-1, group M. subtype D

1

35.8

18.0

24.1

22.1

HIV-1, group O

4

35.0 ± 0.2

19.0 ± 0.1

23.8 ± 0.2

22.2 ± 0.2

HIV-1, group N

8 (gag-pol-env only)

36.0 ± 0.2

17.6 ± 0.2

24.0 ± 0.1

22.2 ± 0.2

HIV-1, group P

1

33.9

18.5

24.6

22.7

SIVchimpanzee

7

35.3 ± 0.5

18.3 ± 0.2

23.8 ± 0.3

22.5 ± 0.2

SIVgorilla

4

34.6 ± 0.0

18.5 ± 0.1

24.6 ± 0.1

22.3 ± 0.2

SIVmangabey

3

34.0 ± 0.2

18.9 ± 0.2

25.1 ± 0.3

22.1 ± 0.4

SIVgreen monkey

9

33.6 ± 0.6

19.3 ± 0.7

25.0 ± 0.5

22.0 ± 0.3

SIVmandrill

3

34,6 ± 1.3

18.1 ± 1.8

24.5 ± 0.6

22.9 ± 1.1

HIV-2

16

33.9 ± 0.3

20.4 ± 0.5

24.9 ± 0.3

20.7 ± 0.5

pSIV (lemur endogenous lentivirus)

1a

29.0

20.5

27.5

23.1

Non-primate lentivirus

     

EAIV

25

35.7 ± 0.2

16.0 ± 0.3

22.0 ± 0.2

26.4 ± 0.4

CAEV/Ovine lentivirusb

7/4

38.0 ± 0.5

15.7 ± 0.6

25.2 ± 0.4

21.1 ± 0.4

CAEV subtype E

2

33.9 ± 0.3

28.1 ± 0.0

28.1 ± 0.2

19.5 ± 0.0

Maedi-visna virus

6

37.2 ± 0.2

26.0 ± 0.1

26.0 ± 0.1

21.4 ± 0.0

Jembrana disease virus

1

31.7

20.1

26.4

21.9

BIV

1

31.8

21.2

23.8

23.2

FIV cat/cougar

4/14

38.0 ± 0.3

14.9 ± 0.1

22.0 ± 0.3

25.2 ± 0.3

FIV Pallas’ cat/lionc

1/2

38.0 ± 0.1

13.7 ± 0.3

22.1 ± 0.3

26.2 ± 0.6

RELIK (hare endogenous lentivirus)d

1 (gag-pol-env only)

34.0

19.4

22.4

24.1

ELVmpf (ferret endogenous lentivirus)

1

33.6

20.0

23.6

22.8

  1. a Consensus sequence of pSIVgml (gray mouse lemur, one proviral copy) and pSIVfdl (fat-tail mouse lemur, several proviral copies).
  2. b Viruses labeled CAEV subtype E and Maedi-visna virus, respectively, different significantly in nucleotide composition from other CAEV types including viruses labeled ovine lentivirus.
  3. c FIV isolated from cats and cougars is phylogenetically distinct from FIV found in Pallas’ cat and lions.
  4. d Similar frequencies for rabbit endogenous retrovirus sequences.
  5. Std = standard deviation.