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Figure 2 | Retrovirology

Figure 2

From: The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies

Figure 2

Neutralization of pseudovirions carrying either NL4.3wt or NL4.3 T373R envelopes. NL4.3 T373R carries a blocked W100 pocket. Env+ pseudovirions were treated with serial dilutions of each mab and residual infectivity evaluated on HeLa TZM-bl cells using luminescence readouts [8]. Mab dilutions are recorded as μg/ml except for gp68 and ICR39.13, which are hybridoma supernatant dilutions. Each data point shown was obtained from averaging readings obtained from two independent neutralization tests each with duplicate points.

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