Figure 8

Analysis of 3’ half HIV-1 genome sequences obtained by by SGA. The 3’ half genome (4685 bp) was amplified by SGA from 47 viruses after five passages of the T/F virus. The Highlighter plot denotes the location of nucleotide substitutions compared to the T/F sequence, with their positions in the vif, vpr, vpu, tat, rev, env and nef genes indicated at the bottom. The T/F sequence is indicated by thicker lines at the top. Nucleotide substitutions are color coded.