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Figure 6 | Retrovirology

Figure 6

From: Caveolin-1 reduces HIV-1 infectivity by restoration of HIV Nef mediated impairment of cholesterol efflux by apoA-I

Figure 6

Cav-1 over-expression inhibits HIV-1 infectivity. MDMs were infected with AD8 or ADnefmut at an moi of 0.1 alone or in combination with Ad-Cav-1 or Ad-GFP. (A) The levels of GFP and Cav-1 expression are shown. (B) and (C) Infectious particles harvested from culture supernatants were titered and normalized. Level of infectivity was measured by infecting TZM-bl cells and subsequent luciferase assay. All experiments were performed in triplicate and results shown are mean ± SD with P values.

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Retrovirology

ISSN: 1742-4690

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