| Model 1 | Model 2 |
---|
Factors | log VL (95% CI) | p-value | log VL (95% CI) | p-value |
---|
log10F
PI
| 0.298 (0.122 – 0.421) | 0.000 | 0.269 (0.105 – 0.433) | 0.001 |
log10F
RTI
| -0.090 (-0.324 – 0.144) | 0.449 | -0.219 (-0.583 – 0.144) | 0.237 |
Factors
|
sqrt CD4 (95% CI)
|
p-value
|
sqrt CD4 (95% CI)
|
p-value
|
log10F
PI
| -2.038 (-3.556 – -0.521) | 0.009 | -1.947 (-3.446 – -0.448) | 0.011 |
log10F
RTI
| 1.220 (-2.145 – 4.585) | 0.477 | 1.243 (-2.074 – 4.560) | 0.462 |
- Linear regression analyses of the association between genotypic predictors and clinical parameters. Patients that did show genotypic evidence of TDR were excluded from the analysis. For each of the genotypic predictors, two models including different sets of potential confounders were performed. Model 1 included genotypic predictors for PR and RT, and estimated duration of infection. Model 2 additionally included age, sex, risk group and area of origin.