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Table 1 Characteristics of HIV-1 subtype B patients included in the analyses for prediction of viral load and CD4 cell count

From: Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

Characterististics Subtype B patients (N = 1599) TDR (N = 151) Wild-type (N = 1446)
log10 HIV-RNA copies/ml 4.85 (4.32 – 5.35) 4.83 (4.30 – 5.33) 4.86 (4.32 – 5.35)
CD4 cells/mm3 382 (212 – 583) 410 (249 – 582) 377 (209 – 583)
Age, years 35 (29 – 42) 34 (28 – 40) 35 (30 – 42)
Male sex , n (%) 1413 (89%) 137 (91%) 1276 (89%)
Duration of infection, n (%)    
     < 1 year 541 (34%) 57 (37%) 484 (33%)
     Undefined 1056 (66%) 94 (63%) 962 (67%)
Source of HIV-1exposure, n (%)    
     Homo/bisexual contact 1016 (65%) 104 (69%) 912 (63%)
     Heterosexual contact 123 (20%) 26 (17%) 290 (20%)
     Intravenous drug use 316 (8%) 8 (5%) 115 (8%)
     Other 142 (9%) 13 (9%) 129 (9%)
Area of origin, n (%)    
     Western Europe 1147 (72%) 105 (70%) 1042 (72%)
     Eastern Europe & Central Asia 282 (18%) 27 (19%) 255 (18%)
     Other 168 (10%) 19 (11%) 149 (10%)
  1. Patient characteristics are shown for the subtype B study dataset (N = 1599), including patients with genotypic evidence of transmitted drug resistance (TDR) and patients without genotypic evidence of transmitted drug resistance (wild-type). Data are expressed as median values accompanied by interquartile ranges, or as number of patients accompanied by proportion of the subtype B dataset (%).