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Figure 1 | Retrovirology

Figure 1

From: Human immunodeficiency virus type 1 envelope proteins traffic toward virion assembly sites via a TBC1D20/Rab1-regulated pathway

Figure 1

Overexpression of TBC1D20 decreases HIV-1 VLPs infectivity. HIV-1 VLPs, pseudotyped with either VSV-G (A) or JRCSF (B) glycoproteins, were generated in 293T cells (~5 × 106 cells/60 mm plate), overexpressing TBC1D20, R105A, or empty vector. HeLa TZM-bl cells were infected with equal amounts of these VLPs and the number of GFP+ cells per 5,000 cells was determined by FACS. The data are represented as the mean ± the standard error of the mean (SEM, n = 3).

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