Figure 3

Profiles of host proteins associated with the cores of HIV-1 virions from different producer cells – data of LC-MS/MS analysis. A, B – Venn Diagrams depicting the number of overlapping cellular proteins within viral cores among the three producer cell types (A) and within the cores of viruses produced by the same cell type (Sup-T1) infected with HIV-1 NL4-3 strain pseudotyped with MLV Env (yellow) or VSV-G (green) envelope glycoproteins (B). The number of non-overlapping proteins and percent of these proteins within all cellular proteins identified in the core are shown as a numerator and denominator respectively. C – Categories of cellular proteins (by function) depicted as a percentage of the total proteins that were identified within the cores of virions produced by Sup-T1 (C1, n = 125), THP1 cells activated with PMA and vitamin D₃ (C2, n = 110), and non-activated THP1 cells (C3, n = 90). The diagram of overlapping cellular proteins detected in all core preparations is shown on C4 (n = 42).