|
Recipient cells
|
Virus
|
Trial 1
|
Trial 2
|
Trial 3
|
Trial 4
|
Ave ± Std
|
Ave
|
|---|
|
IU/ml*
|
IU/ml
|
IU/ml
|
IU/ml
|
IU/ml
|
Relative infectivity**
|
MX/XMRV
|
|---|
|
HeLa
|
XMRV
|
1.0 X 105
|
8.8 X 104
|
1.6 X 105
|
8.0 X 104
|
1.1 ± 0.38 X 105
|
1 ± 0
|
36.0
|
| |
MX
|
4.3 X 106
|
3.1 X 106
|
4.5 X 106
|
3.1 X 106
|
3.8 ± 0.78 X 106
|
36.0 ± 6.52
|
|
293
|
XMRV
|
5.9 X 105
|
1.2 X 106
|
1.4 X 106
| |
1.1 ± 0.42 X 106
|
9.24 ± 3.64
|
3.89
|
| |
MX
|
3.5 X 106
|
4.2 X 106
|
4.2 X 106
| |
3.9 ± 0.38 X 106
|
35.9 ± 11.1
|
|
HepG2
|
XMRV
| |
8.7 X 105
|
2.0 X 106
|
9.6 X 105
|
1.3 ± 0.63 X 106
|
11.4 ± 1.28
|
2.95
|
| |
MX
| |
2.0 X 106
|
7.7 X 106
|
2.5 X 106
|
4.1 ± 3.2 X 106
|
33.6 ± 12.4
|
|
NRK
|
XMRV
|
1.2 X 105
|
2.9 X 104
| | |
7.4 ± 6.3 X 104
|
0.754 ± 0.593
|
14.5
|
| |
MX
|
1.2 X 106
|
8.4 X 105
| | |
1.0 ± 0.29 X 106
|
10.9 ± 2.01
|
|
DU145
|
XMRV
|
8.4 X 103
|
5.1 X 103
| | |
6.7 ± 2.3 X 103
|
0.0705 ± 0.0176
|
20.8
|
| |
MX
|
1.5 X 105
|
1.2 X 105
| | |
1.4 ± 0.21 X 105
|
1.47 ± 0.0846
| |
- The several cell lines were infected with XMRV or MX viruses that were produced from the infected 293 T cells (293 T/XMRV and 293 T/MX). *The infectious units (IU) were measured from the number of infectious centers that was normalized by the amount of Capsid in viruses and IU per ml was shown. **The relative infectivity to HeLa cells infected with XMRV viruses was shown.
