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Table 1 The mutations disrupting expression of putative glyco-gag proteins in XMRV

From: Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms

Constructs

mutation

XMRV p53

XMRV p58

pVP62 (WT)

None

+

+

pVP62Δgg0

_ to A (nt 372)

-

-

pVP62Δgg1

C to AT (nt 382)

-

-

pVP62Δgg2

T to C (nt 370)

+

-

pVP62Δgg3

T to C (nt 341)

-

+

pVP62Δgg4

T to G (nt 354)

-

+

  1. The mutations to disrupt expression of putative glyco-gag proteins, p53 and p58, in the leader sequence region of XMRV VP62 are shown. Reference for original sequence is EF185282.
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Retrovirology

ISSN: 1742-4690

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