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Table 2 Serological responses following immunisation with HIV-1 W61D rgp120

From: Heterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model

GROUP ID NO. VACCINE SEROLOGICAL RESPONSES
    Binding Antibodies(log10 reciprocal titre) Virus Neutralisation Activity(50% virus inhibition log10 titre)
    W61D rgp120 week 50a IIIB rgp120 DOCa SHIVW61DDOCa SHIVW61D
week 50a
SHIVsbgDOCa SHIV-4 DOCa SHIVSF33week 50a SHIVSF33week140a
A A71 30μg W61D rgp120/AS02A i.m 3.9 3.5 2.9   <1 1.6   
  A75   3.9 3.7 3.1   <1 1.5   
  A76   4.2 3.8 3.1   <1 1.2   
  A78   4.1 3.5 3.2   <1 1.4   
C B234 AS02A i.m      <1    
  B235       <1    
  B236       <1    
  B237       <1    
B A72 30μg W61D rgp120/AS02A i.m 4.0    2.7   1.5 1.5  
  A73   3.9    2.7   1.4 1.4  
  A74   4.0    2.7   1.5 1.5  
  A77   4.3    2.3   1.6 1.6  
D B238 AS02A i.m         2.4
  B239          >2.7
  B240          2.2
  B241          >3.4
  1. DOC = day of challenge.
  2. a = time of sampling.