Table 2 Serological responses following immunisation with HIV-1 W61D rgp120
| GROUP | ID NO. | VACCINE | SEROLOGICAL RESPONSES | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Binding Antibodies(log10 reciprocal titre) | Virus Neutralisation Activity(50% virus inhibition log10 titre) | |||||||||
| W61D rgp120 week 50a | IIIB rgp120 DOCa | SHIVW61DDOCa |
SHIVW61D week 50a | SHIVsbgDOCa | SHIV-4 DOCa | SHIVSF33week 50a | SHIVSF33week140a | |||
| A | A71 | 30μg W61D rgp120/AS02A i.m | 3.9 | 3.5 | 2.9 | <1 | 1.6 | |||
| A75 | 3.9 | 3.7 | 3.1 | <1 | 1.5 | |||||
| A76 | 4.2 | 3.8 | 3.1 | <1 | 1.2 | |||||
| A78 | 4.1 | 3.5 | 3.2 | <1 | 1.4 | |||||
| C | B234 | AS02A i.m | <1 | |||||||
| B235 | <1 | |||||||||
| B236 | <1 | |||||||||
| B237 | <1 | |||||||||
| B | A72 | 30μg W61D rgp120/AS02A i.m | 4.0 | 2.7 | 1.5 | 1.5 | ||||
| A73 | 3.9 | 2.7 | 1.4 | 1.4 | ||||||
| A74 | 4.0 | 2.7 | 1.5 | 1.5 | ||||||
| A77 | 4.3 | 2.3 | 1.6 | 1.6 | ||||||
| D | B238 | AS02A i.m | 2.4 | |||||||
| B239 | >2.7 | |||||||||
| B240 | 2.2 | |||||||||
| B241 | >3.4 | |||||||||