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Table 3 Logistic Regression for predicting transmission based on number of conserved glycosites

From: Application of a case–control study design to investigate genotypic signatures of HIV-1 transmission

  Univariate Odd Ratio (95% confidence interval) p-value   Odds Ratio with subtype interaction (95% confidence interval) p-value Test for Homogeneity between subtype, p-value Wilcoxon Rank-Sum, p-value
PNGs in C1   PNGs in C1     
0 to 1    Subtype B  0 to 1     0.538
2    2 0.78 (0.34, 1.74) 0.538   
    Subtype  C 0 to 1     0.661
    2 2.63 (0.20, 34.07) 0.46 0.45  
PNGs in C2   PNGs in C2     
0    Subtype B  0     1
1 0.66 (0.18, 2.38) 0.522 1 1.0 (0.14, 7.28) 1   
    Subtype C  0     0.403
    1 0.48 (0.03, 6.74) 0.587 0.587  
PNGs in C3    PNGs in C3     
0 to 5    Subtype B  0 to 5 0.81 (0.29, 2.24) 0.68   0.669
6 0.76 (0.34, 1.72) 0.51 6 1.36 (0.50, 3.70) 0.551   
7 0.79 (0.36, 1.73) 0.558 7 0.56 (0.14, 2.26) 0.411   
8 0.58 (0.21, 1.62) 0.302 8     
    Subtype C  0 to 5     0.142
    6 0.86 (0.15, 4.85) 0.863   
    7 0.26 (0.05, 1.37) 0.113   
    8 0.90 (0.11, 7.51) 0.922 0.214  
PNGs in C4    PNGs in C4     
0 to 3    Subtype B  0 to 3     0.772
4 0.93 (0.51, 1.71) 0.818 4 1.03 (0.41, 2.58) 0.952   
5 079 (0.43, 1.46) 0.446 5 1.13 (0.48, 2.65) 0.782   
    Subtype C  0 to 3     0.148
    4 0.87 (0.25, 2.96) 0.818   
    5 0.23 (0.05, 1.09) 0.064 0.107  
PNGs in C5   PNGs in C5     
0    Subtype  B 0     0.518
1 1.02 (0.25, 4.23) 0.974 1 0.49 (0.09, 2.78) 0.423   
2 0.96 (0.22, 4.06) 0.951 2 0.44 (0.06, 3.16) 0.413   
    Subtype C  0     0.951
    1     
    2    0.532  
  1. Note: In groups where no sequences have 0 glycosites, logistic regression cannot be performed.