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Figure 3 | Retrovirology

Figure 3

From: Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients

Figure 3

NanoString profiling indicates differential regulation of specific miRNAs. Most differentially expressed miRNAs were downregulated in viremic samples (A), although upregulated miRNAs were also observed (B). The final panel in (A) shows the geometric mean of the three miR-29 family members for each sample. Quantile normalized values for miRNA species in each sample were plotted as fold change in comparison with the mean expression of each respective miRNA within the uninfected control group. Significance was assessed by Kruskal-Wallis test followed by Dunn's multiple comparison test, using the absolute distance of normalized expression values from the control mean. Asterisks represent p-values: * = p < 0.05; ** = p < 0.01, *** = p < 0.001.

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Retrovirology

ISSN: 1742-4690

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