Skip to main content
Figure 5 | Retrovirology

Figure 5

From: HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+T cells in virus-infected individuals

Figure 5

Detailed characterizations of CD4+T-cell subsets in HAM/TSP patients. Freshly isolated PBMCs from HAM/TSP patients (n = 10) were stained with anti-CD4, anti-CD45RA, anti-FoxP3 antibodies and analyzed by flow cytometry. To detect Tax expression, PBMCs were cultivated for 18 hours before antibody staining. (A) Percentages of CD4+ or CD8+ T cells in HAM/TSP patients. (B) Tax positivity of CD4+, CD8+, non-T, FoxP3−, or FoxP3+ cell populations in HAM/TSP patients. (C) Expression levels of Treg associated molecules in FoxP3+ cells of HD or HAM/TSP patients. (D–F) Frequencies of the FoxP3+CD4+ T-cell subset in HD and HAM/TSP patients. Percentages of rTreg cells (D), aTreg cells (E), and FoxP3low non-Treg cells (F) in CD4+ T cells are shown. (G) Tax positivity of each CD4+ T-cell subset in HAM/TSP patients

Back to article page