Figure 1

CD4⁺T-cell subset in HTLV-1 infected individuals. (A) Percentages of CD4⁺ T cells in 4 distinct subjects. Data shown are gated on lymphocyte fraction based on the dot plot pattern of SSC and FSC. (B and C) Proportion of FoxP3⁻CD45RA⁺ naïve CD4⁺ T cells (B) or FoxP3⁻CD45RA⁻ effector/memory CD4⁺ T cells (C). (D) Percentages of FoxP3⁺ cells in CD4⁺ T cells. (E) Frequency of FoxP3⁺CD4⁺ cells in ACs or HAM/TSP patients showed significant correlation with HTLV-1 proviral load by Spearman’s rank correlation (P = 0.0051 or P = 0.0268, r = 0.60 or r = 0.7012, respectively).