Figure 4

Prolonged survival of CD4 + CD45RO + T-cells in GC as compared to follicular T-cell zones and lamina propria. (A-D) Duodenal sections from controls (Ctl) and macaques infected at 14dpi and 28dpi were stained with CD20 mAb (A), CD4 mAb (B), CD45RO mAb (C-D). In A to D, data from one representative macaque per group are shown. Original magnification x100 for panels A to C, x200 for panel D. (E-G) Each symbol corresponds to the mean density of CD45RO⁺ cells per μm2 of duodenal muscularis mucosae (MM, G ), of follicular T-cell zone (F) and to the mean number of CD45R0⁺ cells per GC (E) per macaque. Bars represent median values for each group. * p values <0.05 (Mann–Whitney).