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Table 1 Summary table of the different receptors and eicosanoid-producing enzymes known to be found in the CNS and discussed in this review.

From: Interactions between prostaglandins, leukotrienes and HIV-1: Possible implications for the central nervous system

Cells

Receptors

Enzymes

Microglia

cysLT1 131

COX-2 123, 127, 135, 138

 

cysLT2 124

5-LO 124, 125, 132

 

EP4 141

FLAP 132

 

EP2 141

COX-1 128, 135, 137

  

PLA2 27

Astrocytes

EP2 141

5-LO 133

  

COX-2 138

  

PLA2 129

  

12-LO 130

Oligodendrocytes

GPR17 145

COX-2 138

  

12-LO 130

Neurons

BLT1 131

5-LO 133, 135

 

GPR17 89, 145

COX-2 128, 134

 

cysLT2 144

12-LO 130

 

EP2 141

 
 

EP1 141

 
 

EP3 141

 
 

EP4 141

 

Endothelial cells

cysLT2 147

 
 

EP4 141

 

Unspecified

DP1-2128

 

CNS cell types

FP128

 
 

IP128

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