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Table 1 principal characteristics of the main HLA-C variants

From: HLA-C and HIV-1: friends or foes?

HLA-C allele miR418a site/expression[32, 3436, 52, 53, 59] −35 kb SNP[32] Val/Met 304[57, 59] KIR group type[74, 75] CTL restriction Association with control Association with progression Increase of HIV-1 infectivity[92, 93]
01.02 Intact/Low C Val* C1 [69]    NT
02.02 Deleted/High C Val* C2   [53]   NT
03.03, .04 Intact/Low T Val* C1 [63, 66]    Yes
04.01 Intact/Low T Val* C2 [6368]   [34, 37] Yes
05.01 Deleted/High C Met*/Val* C2     NT
06.02 Deleted/High C Met*/Val* C2     NT
07.01, .02, .04 Intact/Low T Val C1 [63, 70]   [36] Yes
08.01, .02, .04 Deleted/High C Met*/Val* C1     NT
12.02, .03 Deleted/High C Met*/Val* C1* [54] [54]   Yes ?**
14.02 Intact/Low C Val* C1*     NT
15.02, .05, .06 Deleted/High T Met*/Val* C2* [63]    NT
16.01, .02, .04 Deleted/High T Val* C1*     NT
17.01 Intact/Low T Val* C2*     NT
  1. *: data obtained by sequence alignment analysis.
  2. **: C*12/C*07.
  3. NT not tested.