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Table 1 Cellular proteins detected exclusively in wild-type Nef immunocomplexes

From: Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation

Accession Gene Protein Description   Unique # peptides
FACS-sorted 5C Nef   
Q9NV70 EXOC1 EXOC1 Exocyst complex component 1, isoform 1   3
Q96KP1 EXOC2 EXOC2 Exocyst complex component 2   3
O60645 EXOC3 EXOC3 Exocyst complex component 3, isoform 1   3
Q96A65 EXOC4 EXOC4 Exocyst complex component 4   6
Q8TAG9 EXOC6 EXOC6 Exocyst complex component 6   1
Q9UL85 a    Myosin-reactive Igκ chain variable region (fragment)   1
P19838 NFKB1 NFKB1 Nuclear factor NF-κB p105 subunit, isoform 2   1
Unsorted 5C Nef   
Q9NV70 EXOC1 EXOC1 Exocyst complex component 1, isoform 1   3
Q96KP1 EXOC2 EXOC2 Exocyst complex component 2   3
O60645 EXOC3 EXOC3 Exocyst complex component 3, isoform 1   2
Q96A65 EXOC4 EXOC4 Exocyst complex component 4   4
Q9NP29 a    Microfibrillar protein 2 (fragment)   1
Q13177 PAK2 Pak2 PAK2 Serine/threonine-protein kinase   3
P60866 RPS20 RS20 40S ribosomal protein S20   1
Gene or Accession D N -score b Z-score b Description Total #peptides Unique # peptides
FACS-sorted and unsorted 5C Nef combined   
EXOC1 7.14 10.09 Exocyst complex component 1, isoform 1 6 5
EXOC2 7.14 10.09 Exocyst complex component 2 6 5
EXOC3 5.83 10.09 Exocyst complex component 3, isoform 1 4 4
EXOC4 9.21 10.10 Exocyst complex component 4 10 6
EXOC6 0.41 10.05 Exocyst complex component 6 1 1
NFKB1 0.05 −0.59 Nuclear factor NF-κB p105 subunit, isoform 2 1 1
PAK2 0.70 10.09 PAK2 Serine/threonine-protein kinase 3 3
Q9NP29 a 0.41 10.05 Microfibrillar protein 2 (fragment) 1 1
Q9UL85 a 0.41 10.05 Myosin-reactive Igκ chain variable region (fragment) 1 1
RPS20 0.04 −1.51 40S ribosomal protein S20 1 1
  1. a) Unreviewed entries from UniProtKB/TrEMBL; all other accessions from Swiss-Prot/UniProtKB [57]. b) Statistical scores obtained via CompPASS analysis.