TY - JOUR AU - Arhel, N. J. AU - Kirchhoff, F. PY - 2010 DA - 2010// TI - Implications of nef: host cell interactions in viral persistence and progression to AIDS JO - Curr Top Microbiol Immunol VL - 339 ID - Arhel2010 ER - TY - JOUR AU - Foster, J. AU - Garcia, J. V. PY - 2008 DA - 2008// TI - HIV-1 Nef: at the crossroads JO - Retrovirology VL - 5 UR - https://doi.org/10.1186/1742-4690-5-84 DO - 10.1186/1742-4690-5-84 ID - Foster2008 ER - TY - JOUR AU - Peterlin, B. M. AU - Trono, D. PY - 2003 DA - 2003// TI - Hide, shield and strike back: how HIV-infected cells avoid immune eradication JO - Nat Rev Immunol VL - 3 UR - https://doi.org/10.1038/nri998 DO - 10.1038/nri998 ID - Peterlin2003 ER - TY - JOUR AU - Roeth, J. F. AU - Collins, K. L. PY - 2006 DA - 2006// TI - Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways JO - Microbiol Mol Biol Rev VL - 70 UR - https://doi.org/10.1128/MMBR.00042-05 DO - 10.1128/MMBR.00042-05 ID - Roeth2006 ER - TY - JOUR AU - Wei, B. L. AU - Arora, V. K. AU - Foster, J. L. AU - Sodora, D. L. AU - Garcia, J. V. PY - 2003 DA - 2003// TI - In vivo analysis of Nef function JO - Curr HIV Res VL - 1 UR - https://doi.org/10.2174/1570162033352057 DO - 10.2174/1570162033352057 ID - Wei2003 ER - TY - JOUR AU - Fenard, D. AU - Yonemoto, W. AU - de Noronha, C. AU - Cavrois, M. AU - Williams, S. A. AU - Greene, W. C. PY - 2005 DA - 2005// TI - Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagemen JO - J Immunol (Baltimore, Md: 1950) VL - 175 UR - https://doi.org/10.4049/jimmunol.175.9.6050 DO - 10.4049/jimmunol.175.9.6050 ID - Fenard2005 ER - TY - JOUR AU - Schrager, J. A. AU - Marsh, J. W. PY - 1999 DA - 1999// TI - HIV-1 Nef increases T cell activation in a stimulus-dependent manner JO - Proceedings of the National Academy of Sciences of the United States VL - 96 UR - https://doi.org/10.1073/pnas.96.14.8167 DO - 10.1073/pnas.96.14.8167 ID - Schrager1999 ER - TY - JOUR AU - Simmons, A. AU - Aluvihare, V. AU - McMichael, A. PY - 2001 DA - 2001// TI - Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators JO - Immunity VL - 14 UR - https://doi.org/10.1016/S1074-7613(01)00158-3 DO - 10.1016/S1074-7613(01)00158-3 ID - Simmons2001 ER - TY - JOUR AU - Costa, L. J. AU - Chen, N. AU - Lopes, A. AU - Aguiar, R. S. AU - Tanuri, A. AU - Plemenitas, A. AU - Peterlin, B. M. PY - 2006 DA - 2006// TI - Interactions between Nef and AIP1 proliferate multivesicular bodies and facilitate egress of HIV-1 JO - Retrovirology VL - 3 UR - https://doi.org/10.1186/1742-4690-3-33 DO - 10.1186/1742-4690-3-33 ID - Costa2006 ER - TY - JOUR AU - Peterlin, B. M. PY - 2006 DA - 2006// TI - Nef: out and in? JO - Nat Immunol VL - 7 UR - https://doi.org/10.1038/ni0306-229 DO - 10.1038/ni0306-229 ID - Peterlin2006 ER - TY - JOUR AU - Stumptner-Cuvelette, P. AU - Jouve, M. AU - Helft, J. AU - Dugast, M. AU - Glouzman, A. S. AU - Jooss, K. AU - Raposo, G. AU - Benaroch, P. PY - 2003 DA - 2003// TI - Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase JO - Mol Biol Cell VL - 14 UR - https://doi.org/10.1091/mbc.E03-04-0211 DO - 10.1091/mbc.E03-04-0211 ID - Stumptner-Cuvelette2003 ER - TY - JOUR AU - Rudnicka, D. AU - Schwartz, O. PY - 2009 DA - 2009// TI - Intrusive HIV-1-infected cells JO - Nat Immunol VL - 10 UR - https://doi.org/10.1038/ni0909-933 DO - 10.1038/ni0909-933 ID - Rudnicka2009 ER - TY - JOUR AU - Xu, W. AU - Santini, P. A. AU - Sullivan, J. S. AU - He, B. AU - Shan, M. AU - Ball, S. C. AU - Dyer, W. B. AU - Ketas, T. J. AU - Chadburn, A. AU - Cohen-gould, L. PY - 2009 DA - 2009// TI - HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits JO - Nat Publishing Group VL - 10 ID - Xu2009 ER - TY - JOUR AU - da Silva, L. L. AU - Sougrat, R. AU - Burgos, P. V. AU - Janvier, K. AU - Mattera, R. AU - Bonifacino, J. S. PY - 2009 DA - 2009// TI - Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway JO - J Virol VL - 83 UR - https://doi.org/10.1128/JVI.00548-09 DO - 10.1128/JVI.00548-09 ID - da Silva2009 ER - TY - JOUR AU - Jin, Y. J. AU - Cai, C. Y. AU - Zhang, X. AU - Zhang, H. T. AU - Hirst, J. A. AU - Burakoff, S. J. PY - 2005 DA - 2005// TI - HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent JO - J Immunol VL - 175 UR - https://doi.org/10.4049/jimmunol.175.5.3157 DO - 10.4049/jimmunol.175.5.3157 ID - Jin2005 ER - TY - JOUR AU - Lindwasser, O. W. AU - Smith, W. J. AU - Chaudhuri, R. AU - Yang, P. AU - Hurley, J. H. AU - Bonifacino, J. S. PY - 2008 DA - 2008// TI - A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2 JO - J Virol VL - 82 UR - https://doi.org/10.1128/JVI.01874-07 DO - 10.1128/JVI.01874-07 ID - Lindwasser2008 ER - TY - JOUR AU - Jager, S. AU - Cimermancic, P. AU - Gulbahce, N. AU - Johnson, J. R. AU - McGovern, K. E. AU - Clarke, S. C. AU - Shales, M. AU - Mercenne, G. AU - Pache, L. AU - Li, K. PY - 2012 DA - 2012// TI - Global landscape of HIV-human protein complexes JO - Nature VL - 481 ID - Jager2012 ER - TY - JOUR AU - Craig, H. M. AU - Reddy, T. R. AU - Riggs, N. L. AU - Dao, P. P. AU - Guatelli, J. C. PY - 2000 DA - 2000// TI - Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif JO - Virology VL - 271 UR - https://doi.org/10.1006/viro.2000.0277 DO - 10.1006/viro.2000.0277 ID - Craig2000 ER - TY - JOUR AU - Blagoveshchenskaya, A. D. AU - Thomas, L. AU - Feliciangeli, S. F. AU - Hung, C. H. AU - Thomas, G. PY - 2002 DA - 2002// TI - HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway JO - Cell VL - 111 UR - https://doi.org/10.1016/S0092-8674(02)01162-5 DO - 10.1016/S0092-8674(02)01162-5 ID - Blagoveshchenskaya2002 ER - TY - JOUR AU - Piguet, V. AU - Wan, L. AU - Borel, C. AU - Mangasarian, A. AU - Demaurex, N. AU - Thomas, G. AU - Trono, D. PY - 2000 DA - 2000// TI - HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes JO - Nat Cell Biol VL - 2 UR - https://doi.org/10.1038/35004038 DO - 10.1038/35004038 ID - Piguet2000 ER - TY - JOUR AU - Simons, M. AU - Raposo, G. PY - 2009 DA - 2009// TI - Exosomes–vesicular carriers for intercellular communication JO - Curr Opin Cell Biol VL - 21 UR - https://doi.org/10.1016/j.ceb.2009.03.007 DO - 10.1016/j.ceb.2009.03.007 ID - Simons2009 ER - TY - JOUR AU - Ali, S. A. AU - Huang, M. B. AU - Campbell, P. E. AU - Roth, W. W. AU - Campbell, T. AU - Khan, M. AU - Newman, G. AU - Villinger, F. AU - Powell, M. D. AU - Bond, V. C. PY - 2010 DA - 2010// TI - Genetic characterization of HIV type 1 Nef-induced vesicle secretion JO - AIDS Res Hum Retroviruses VL - 26 UR - https://doi.org/10.1089/aid.2009.0068 DO - 10.1089/aid.2009.0068 ID - Ali2010 ER - TY - JOUR AU - Campbell, T. D. AU - Khan, M. AU - Huang, M. B. AU - Bond, V. C. AU - Powell, M. D. PY - 2008 DA - 2008// TI - HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions JO - Ethn Dis VL - 18 ID - Campbell2008 ER - TY - JOUR AU - Lenassi, M. AU - Cagney, G. AU - Liao, M. AU - Vaupotic, T. AU - Bartholomeeusen, K. AU - Cheng, Y. AU - Krogan, N. J. AU - Plemenitas, A. AU - Peterlin, B. M. PY - 2010 DA - 2010// TI - HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells JO - Traffic (Copenhagen, Denmark) VL - 11 UR - https://doi.org/10.1111/j.1600-0854.2009.01006.x DO - 10.1111/j.1600-0854.2009.01006.x ID - Lenassi2010 ER - TY - JOUR AU - Muratori, C. AU - Cavallin, L. E. AU - Kratzel, K. AU - Tinari, A. AU - Muratori, C. AU - Cavallin, L. E. AU - Kratzel, K. AU - Tinari, A. A. AU - Fais, S. AU - D’Aloja, P. AU - Federico, M. AU - Vullo, V. AU - Fomina, A. PY - 2009 DA - 2009// TI - Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells JO - Cell Host Microbe VL - 6 UR - https://doi.org/10.1016/j.chom.2009.06.009 DO - 10.1016/j.chom.2009.06.009 ID - Muratori2009 ER - TY - JOUR AU - Shelton, M. N. AU - Huang, M. B. AU - Ali, S. A. AU - Powell, M. D. AU - Bond, V. C. PY - 2012 DA - 2012// TI - Secretion modification region-derived peptide disrupts HIV-1 Nef’s interaction with mortalin and blocks virus and Nef exosome release JO - J Virol VL - 86 UR - https://doi.org/10.1128/JVI.05720-11 DO - 10.1128/JVI.05720-11 ID - Shelton2012 ER - TY - JOUR AU - Raymond, A. D. AU - Campbell-Sims, T. C. AU - Khan, M. AU - Lang, M. AU - Huang, M. B. AU - Bond, V. C. AU - Powell, M. D. PY - 2011 DA - 2011// TI - HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals JO - AIDS Res Human Retroviruses VL - 27 UR - https://doi.org/10.1089/aid.2009.0170 DO - 10.1089/aid.2009.0170 ID - Raymond2011 ER - TY - JOUR AU - Arora, V. K. AU - Molina, R. P. AU - Foster, J. L. AU - Blakemore, J. L. AU - Chernoff, J. AU - Fredericksen, B. L. AU - Garcia, J. V. PY - 2000 DA - 2000// TI - Lentivirus Nef specifically activates Pak2 JO - J Virol VL - 74 UR - https://doi.org/10.1128/JVI.74.23.11081-11087.2000 DO - 10.1128/JVI.74.23.11081-11087.2000 ID - Arora2000 ER - TY - JOUR AU - Janardhan, A. AU - Swigut, T. AU - Hill, B. AU - Myers, M. P. AU - Skowronski, J. PY - 2004 DA - 2004// TI - HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis JO - PLoS Biol VL - 2 UR - https://doi.org/10.1371/journal.pbio.0020006 DO - 10.1371/journal.pbio.0020006 ID - Janardhan2004 ER - TY - JOUR AU - Krautkramer, E. AU - Giese, S. I. AU - Gasteier, J. E. AU - Muranyi, W. AU - Fackler, O. T. PY - 2004 DA - 2004// TI - Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.8.4085-4097.2004 DO - 10.1128/JVI.78.8.4085-4097.2004 ID - Krautkramer2004 ER - TY - JOUR AU - Pulkkinen, K. AU - Renkema, G. H. AU - Kirchhoff, F. AU - Saksela, K. PY - 2004 DA - 2004// TI - Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.23.12773-12780.2004 DO - 10.1128/JVI.78.23.12773-12780.2004 ID - Pulkkinen2004 ER - TY - JOUR AU - Renkema, G. H. AU - Manninen, A. AU - Saksela, K. PY - 2001 DA - 2001// TI - Human immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIX JO - J Virol VL - 75 UR - https://doi.org/10.1128/JVI.75.5.2154-2160.2001 DO - 10.1128/JVI.75.5.2154-2160.2001 ID - Renkema2001 ER - TY - JOUR AU - Olivieri, K. C. AU - Mukerji, J. AU - Gabuzda, D. PY - 2011 DA - 2011// TI - Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2 JO - Retrovirology VL - 8 UR - https://doi.org/10.1186/1742-4690-8-64 DO - 10.1186/1742-4690-8-64 ID - Olivieri2011 ER - TY - JOUR AU - Brown, A. AU - Wang, X. AU - Sawai, E. AU - Cheng-Mayer, C. PY - 1999 DA - 1999// TI - Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex JO - J Virol VL - 73 ID - Brown1999 ER - TY - JOUR AU - Fackler, O. T. AU - Luo, W. AU - Geyer, M. AU - Alberts, A. S. AU - Peterlin, B. M. PY - 1999 DA - 1999// TI - Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions JO - Mol Cell VL - 3 UR - https://doi.org/10.1016/S1097-2765(01)80005-8 DO - 10.1016/S1097-2765(01)80005-8 ID - Fackler1999 ER - TY - JOUR AU - Linnemann, T. AU - Zheng, Y. H. AU - Mandic, R. AU - Peterlin, B. M. PY - 2002 DA - 2002// TI - Interaction between Nef and phosphatidylinositol-3-kinase leads to activation of p21-activated kinase and increased production of HIV JO - Virology VL - 294 UR - https://doi.org/10.1006/viro.2002.1365 DO - 10.1006/viro.2002.1365 ID - Linnemann2002 ER - TY - JOUR AU - Rauch, S. AU - Pulkkinen, K. AU - Saksela, K. AU - Fackler, O. T. PY - 2008 DA - 2008// TI - Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity JO - J Virol VL - 82 UR - https://doi.org/10.1128/JVI.02185-07 DO - 10.1128/JVI.02185-07 ID - Rauch2008 ER - TY - JOUR AU - Arold, S. AU - Franken, P. AU - Strub, M. P. AU - Hoh, F. AU - Benichou, S. AU - Benarous, R. AU - Dumas, C. PY - 1997 DA - 1997// TI - The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling JO - Structure VL - 5 UR - https://doi.org/10.1016/S0969-2126(97)00286-4 DO - 10.1016/S0969-2126(97)00286-4 ID - Arold1997 ER - TY - JOUR AU - Greenway, A. AU - Azad, A. AU - Mills, J. AU - McPhee, D. PY - 1996 DA - 1996// TI - Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity JO - J Virol VL - 70 ID - Greenway1996 ER - TY - JOUR AU - Chu, P. C. AU - Wu, J. AU - Liao, X. C. AU - Pardo, J. AU - Zhao, H. AU - Li, C. AU - Mendenhall, M. K. AU - Pali, E. AU - Shen, M. AU - Yu, S. PY - 2004 DA - 2004// TI - A novel role for p21-activated protein kinase 2 in T cell activation JO - J Immunol VL - 172 UR - https://doi.org/10.4049/jimmunol.172.12.7324 DO - 10.4049/jimmunol.172.12.7324 ID - Chu2004 ER - TY - JOUR AU - Fackler, O. T. AU - Alcover, A. AU - Schwartz, O. PY - 2007 DA - 2007// TI - Modulation of the immunological synapse: a key to HIV-1 pathogenesis? JO - Nat Rev Immunol VL - 7 UR - https://doi.org/10.1038/nri2041 DO - 10.1038/nri2041 ID - Fackler2007 ER - TY - JOUR AU - Haller, C. AU - Fackler, O. T. PY - 2008 DA - 2008// TI - HIV-1 at the immunological and T-lymphocytic virological synapse JO - Biol Chem VL - 389 UR - https://doi.org/10.1515/BC.2008.143 DO - 10.1515/BC.2008.143 ID - Haller2008 ER - TY - JOUR AU - Yokosuka, T. AU - Sakata-Sogawa, K. AU - Kobayashi, W. AU - Hiroshima, M. AU - Hashimoto-Tane, A. AU - Tokunaga, M. AU - Dustin, M. L. AU - Saito, T. PY - 2005 DA - 2005// TI - Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76 JO - Nat Immunol VL - 6 UR - https://doi.org/10.1038/ni1272 DO - 10.1038/ni1272 ID - Yokosuka2005 ER - TY - JOUR AU - Blanchard, N. AU - Lankar, D. AU - Faure, F. AU - Regnault, A. AU - Dumont, C. AU - Raposo, G. AU - Hivroz, C. PY - 2002 DA - 2002// TI - TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex JO - J Immunol VL - 168 UR - https://doi.org/10.4049/jimmunol.168.7.3235 DO - 10.4049/jimmunol.168.7.3235 ID - Blanchard2002 ER - TY - JOUR AU - Haller, C. AU - Rauch, S. AU - Fackler, O. T. PY - 2007 DA - 2007// TI - HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling JO - PLoS One VL - 2 UR - https://doi.org/10.1371/journal.pone.0001212 DO - 10.1371/journal.pone.0001212 ID - Haller2007 ER - TY - JOUR AU - Haller, C. AU - Rauch, S. AU - Michel, N. AU - Hannemann, S. AU - Lehmann, M. J. AU - Keppler, O. T. AU - Fackler, O. T. PY - 2006 DA - 2006// TI - The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M513802200 DO - 10.1074/jbc.M513802200 ID - Haller2006 ER - TY - JOUR AU - Arhel, N. AU - Lehmann, M. AU - Clauss, K. AU - Nienhaus, G. U. AU - Piguet, V. AU - Kirchhoff, F. PY - 2009 DA - 2009// TI - The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses JO - J Clin Invest VL - 119 ID - Arhel2009 ER - TY - JOUR AU - Petit, C. AU - Buseyne, F. AU - Boccaccio, C. AU - Abastado, J. -. P. AU - Heard, J. -. M. AU - Schwartz, O. PY - 2001 DA - 2001// TI - Nef Is Required for Efficient HIV-1 Replication in Cocultures of Dendritic Cells and Lymphocytes JO - Virology VL - 286 UR - https://doi.org/10.1006/viro.2001.0984 DO - 10.1006/viro.2001.0984 ID - Petit2001 ER - TY - JOUR AU - Izquierdo-useros, N. AU - Naranjo-go, M. AU - Archer, J. AU - Hatch, S. C. AU - Erkizia, I. AU - Puertas, M. C. AU - Connor, J. H. AU - Ferna, M. T. AU - Moore, L. PY - 2009 DA - 2009// TI - Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway JO - Blood VL - 113 UR - https://doi.org/10.1182/blood-2008-05-158642 DO - 10.1182/blood-2008-05-158642 ID - Izquierdo-useros2009 ER - TY - JOUR AU - Sherer, N. M. AU - Mothes, W. PY - 2008 DA - 2008// TI - Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis JO - Trends Cell Biol VL - 18 UR - https://doi.org/10.1016/j.tcb.2008.07.003 DO - 10.1016/j.tcb.2008.07.003 ID - Sherer2008 ER - TY - JOUR AU - Sowinski, S. AU - Jolly, C. AU - Berninghausen, O. AU - Purbhoo, M. A. AU - Chauveau, A. AU - Kohler, K. AU - Oddos, S. AU - Eissmann, P. AU - Brodsky, F. M. AU - Hopkins, C. PY - 2008 DA - 2008// TI - Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission JO - Nat Cell Biol VL - 10 UR - https://doi.org/10.1038/ncb1682 DO - 10.1038/ncb1682 ID - Sowinski2008 ER - TY - JOUR AU - Van den Broeke, C. AU - Radu, M. AU - Chernoff, J. AU - Favoreel, H. W. PY - 2010 DA - 2010// TI - An emerging role for p21-activated kinases (Paks) in viral infections JO - Trends Cell Biol VL - 20 UR - https://doi.org/10.1016/j.tcb.2009.12.005 DO - 10.1016/j.tcb.2009.12.005 ID - Van den Broeke2010 ER - TY - JOUR AU - Agopian, K. AU - Wei, B. L. AU - Garcia, J. V. AU - Gabuzda, D. PY - 2006 DA - 2006// TI - A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2 JO - J Virol VL - 80 UR - https://doi.org/10.1128/JVI.80.6.3050-3061.2006 DO - 10.1128/JVI.80.6.3050-3061.2006 ID - Agopian2006 ER - TY - JOUR AU - Wang, J. K. AU - Kiyokawa, E. AU - Verdin, E. AU - Trono, D. PY - 2000 DA - 2000// TI - The Nef protein of HIV-1 associates with rafts and primes T cells for activation JO - Proc Natl Acad Sci U S A VL - 97 UR - https://doi.org/10.1073/pnas.97.1.394 DO - 10.1073/pnas.97.1.394 ID - Wang2000 ER - TY - JOUR AU - Sowa, M. E. AU - Bennett, E. J. AU - Gygi, S. P. AU - Harper, J. W. PY - 2009 DA - 2009// TI - Defining the Human Deubiquitinating Enzyme Interaction Landscape JO - Cell VL - 138 UR - https://doi.org/10.1016/j.cell.2009.04.042 DO - 10.1016/j.cell.2009.04.042 ID - Sowa2009 ER - TY - JOUR AU - Jackson, P. K. PY - 2009 DA - 2009// TI - Navigating the Deubiquitinating Proteome with a CompPASS JO - Cell VL - 138 UR - https://doi.org/10.1016/j.cell.2009.07.008 DO - 10.1016/j.cell.2009.07.008 ID - Jackson2009 ER - TY - JOUR PY - 2010 DA - 2010// TI - The Universal Protein Resource (UniProt) in 2010 JO - Nucl Acids Res VL - 38 UR - https://doi.org/10.1093/nar/gkp846 DO - 10.1093/nar/gkp846 ID - ref57 ER - TY - JOUR AU - He, B. AU - Guo, W. PY - 2009 DA - 2009// TI - The exocyst complex in polarized exocytosis JO - Curr Opin Cell Biol VL - 21 UR - https://doi.org/10.1016/j.ceb.2009.04.007 DO - 10.1016/j.ceb.2009.04.007 ID - He2009 ER - TY - JOUR AU - Munson, M. AU - Novick, P. PY - 2006 DA - 2006// TI - The exocyst defrocked, a framework of rods revealed JO - Nat Struct Mol Biol VL - 13 UR - https://doi.org/10.1038/nsmb1097 DO - 10.1038/nsmb1097 ID - Munson2006 ER - TY - JOUR AU - Fortin, J. F. AU - Barat, C. AU - Beausejour, Y. AU - Barbeau, B. AU - Tremblay, M. J. PY - 2004 DA - 2004// TI - Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M407477200 DO - 10.1074/jbc.M407477200 ID - Fortin2004 ER - TY - JOUR AU - Witte, V. AU - Laffert, B. AU - Gintschel, P. AU - Krautkramer, E. AU - Blume, K. AU - Fackler, O. T. AU - Baur, A. S. PY - 2008 DA - 2008// TI - Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of ERK1/2 but not NF kappa B JO - J Immunol VL - 181 UR - https://doi.org/10.4049/jimmunol.181.12.8425 DO - 10.4049/jimmunol.181.12.8425 ID - Witte2008 ER - TY - JOUR AU - Tuosto, L. AU - Marinari, B. AU - Andreotti, M. AU - Federico, M. AU - Piccolella, E. PY - 2003 DA - 2003// TI - Vav exchange factor counteracts the HIV-1 Nef-mediated decrease of plasma membrane GM1 and NF-AT activity in T cells JO - Eur J Immunol VL - 33 UR - https://doi.org/10.1002/eji.200323682 DO - 10.1002/eji.200323682 ID - Tuosto2003 ER - TY - JOUR AU - Lipschutz, J. H. AU - Lingappa, V. R. AU - Mostov, K. E. PY - 2003 DA - 2003// TI - The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M213210200 DO - 10.1074/jbc.M213210200 ID - Lipschutz2003 ER - TY - JOUR AU - von Mering, C. AU - Jensen, L. J. AU - Snel, B. AU - Hooper, S. D. AU - Krupp, M. AU - Foglierini, M. AU - Jouffre, N. AU - Huynen, M. A. AU - Bork, P. PY - 2005 DA - 2005// TI - STRING: known and predicted protein-protein associations, integrated and transferred across organisms JO - Nucleic Acids Res VL - 33 UR - https://doi.org/10.1093/nar/gki005 DO - 10.1093/nar/gki005 ID - von Mering2005 ER - TY - JOUR AU - Fielding, A. B. AU - Schonteich, E. AU - Matheson, J. AU - Wilson, G. AU - Yu, X. AU - Hickson, G. R. AU - Srivastava, S. AU - Baldwin, S. A. AU - Prekeris, R. AU - Gould, G. W. PY - 2005 DA - 2005// TI - Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis JO - EMBO J VL - 24 UR - https://doi.org/10.1038/sj.emboj.7600803 DO - 10.1038/sj.emboj.7600803 ID - Fielding2005 ER - TY - JOUR AU - Hase, K. AU - Kimura, S. AU - Takatsu, H. AU - Ohmae, M. AU - Kawano, S. AU - Kitamura, H. AU - Ito, M. AU - Watarai, H. AU - Hazelett, C. C. AU - Yeaman, C. AU - Ohno, H. PY - 2009 DA - 2009// TI - M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex JO - Nat Cell Biol VL - 11 UR - https://doi.org/10.1038/ncb1990 DO - 10.1038/ncb1990 ID - Hase2009 ER - TY - JOUR AU - Sowinski, S. AU - Alakoskela, J. M. AU - Jolly, C. AU - Davis, D. M. PY - 2010 DA - 2010// TI - Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1 JO - Methods VL - 53 UR - https://doi.org/10.1016/j.ymeth.2010.04.002 DO - 10.1016/j.ymeth.2010.04.002 ID - Sowinski2010 ER - TY - JOUR AU - Ndolo, T. AU - George, M. AU - Nguyen, H. AU - Dandekar, S. PY - 2006 DA - 2006// TI - Expression of simian immunodeficiency virus Nef protein in CD4+ T cells leads to a molecular profile of viral persistence and immune evasion JO - Virology VL - 353 UR - https://doi.org/10.1016/j.virol.2006.06.008 DO - 10.1016/j.virol.2006.06.008 ID - Ndolo2006 ER - TY - JOUR AU - Hyrcza, M. D. AU - Kovacs, C. AU - Loutfy, M. AU - Halpenny, R. AU - Heisler, L. AU - Yang, S. AU - Wilkins, O. AU - Ostrowski, M. AU - Der, S. D. PY - 2007 DA - 2007// TI - Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells JO - J Virol VL - 81 UR - https://doi.org/10.1128/JVI.01552-06 DO - 10.1128/JVI.01552-06 ID - Hyrcza2007 ER - TY - JOUR AU - Madrid, R. AU - Janvier, K. AU - Hitchin, D. AU - Day, J. AU - Coleman, S. AU - Noviello, C. AU - Bouchet, J. AU - Benmerah, A. AU - Guatelli, J. AU - Benichou, S. PY - 2005 DA - 2005// TI - Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M401202200 DO - 10.1074/jbc.M401202200 ID - Madrid2005 ER - TY - JOUR AU - Zhao, Z. -. S. AU - Lim, J. P. AU - Ng, Y. -. W. AU - Lim, L. AU - Manser, E. PY - 2005 DA - 2005// TI - The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A JO - Mol Cell VL - 20 UR - https://doi.org/10.1016/j.molcel.2005.08.035 DO - 10.1016/j.molcel.2005.08.035 ID - Zhao2005 ER - TY - JOUR AU - Moskalenko, S. AU - Tong, C. AU - Rosse, C. AU - Mirey, G. AU - Formstecher, E. AU - Daviet, L. AU - Camonis, J. AU - White, M. A. PY - 2003 DA - 2003// TI - Ral GTPases regulate exocyst assembly through dual subunit interactions JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M308702200 DO - 10.1074/jbc.M308702200 ID - Moskalenko2003 ER - TY - JOUR AU - Lim, K. -. H. AU - Brady, D. C. AU - Kashatus, D. F. AU - Ancrile, B. B. AU - Der, C. J. AU - Cox, A. D. AU - Counter, C. M. PY - 2010 DA - 2010// TI - Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA JO - Mol Cell Biol VL - 30 UR - https://doi.org/10.1128/MCB.00916-08 DO - 10.1128/MCB.00916-08 ID - Lim2010 ER - TY - JOUR AU - Hertzog, M. AU - Chavrier, P. PY - 2011 DA - 2011// TI - Cell polarity during motile processes: keeping on track with the exocyst complex JO - Biochem J VL - 433 UR - https://doi.org/10.1042/BJ20101214 DO - 10.1042/BJ20101214 ID - Hertzog2011 ER - TY - JOUR AU - Zuo, X. AU - Zhang, J. AU - Zhang, Y. AU - Hsu, S. C. AU - Zhou, D. AU - Guo, W. PY - 2006 DA - 2006// TI - Exo70 interacts with the Arp2/3 complex and regulates cell migration JO - Nat Cell Biol VL - 8 UR - https://doi.org/10.1038/ncb1505 DO - 10.1038/ncb1505 ID - Zuo2006 ER - TY - JOUR AU - Grant, B. D. AU - Donaldson, J. G. PY - 2009 DA - 2009// TI - Pathways and mechanisms of endocytic recycling JO - Nat Rev Mol Cell Biol VL - 10 UR - https://doi.org/10.1038/nrm2755 DO - 10.1038/nrm2755 ID - Grant2009 ER - TY - JOUR AU - Chaudhry, A. AU - Das, S. R. AU - Jameel, S. AU - George, A. AU - Bal, V. AU - Mayor, S. AU - Rath, S. PY - 2008 DA - 2008// TI - HIV-1 Nef induces a Rab11-dependent routing of endocytosed immune costimulatory proteins CD80 and CD86 to the Golgi JO - Traffic (Copenhagen, Denmark) VL - 9 UR - https://doi.org/10.1111/j.1600-0854.2008.00802.x DO - 10.1111/j.1600-0854.2008.00802.x ID - Chaudhry2008 ER - TY - JOUR AU - Zhang, X. M. AU - Ellis, S. AU - Sriratana, A. AU - Mitchell, C. A. AU - Rowe, T. PY - 2004 DA - 2004// TI - Sec15 is an effector for the Rab11 GTPase in mammalian cells JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M402264200 DO - 10.1074/jbc.M402264200 ID - Zhang2004 ER - TY - JOUR AU - Alexander, M. AU - Bor, Y. C. AU - Ravichandran, K. S. AU - Hammarskjold, M. L. AU - Rekosh, D. PY - 2004 DA - 2004// TI - Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.4.1685-1696.2004 DO - 10.1128/JVI.78.4.1685-1696.2004 ID - Alexander2004 ER - TY - JOUR AU - Balasubramanian, N. AU - Meier, J. A. AU - Scott, D. W. AU - Norambuena, A. AU - White, M. A. AU - Schwartz, M. A. PY - 2010 DA - 2010// TI - RalA-Exocyst Complex Regulates Integrin-Dependent Membrane Raft Exocytosis and Growth Signaling JO - Curr Biol VL - 20 UR - https://doi.org/10.1016/j.cub.2009.11.016 DO - 10.1016/j.cub.2009.11.016 ID - Balasubramanian2010 ER - TY - JOUR AU - Zhou, H. AU - Xu, M. AU - Huang, Q. AU - Gates, A. T. AU - Zhang, X. D. AU - Castle, J. C. AU - Stec, E. AU - Ferrer, M. AU - Strulovici, B. AU - Hazuda, D. J. AU - Espeseth, A. S. PY - 2008 DA - 2008// TI - Genome-scale RNAi screen for host factors required for HIV replication JO - Cell Host Microbe VL - 4 UR - https://doi.org/10.1016/j.chom.2008.10.004 DO - 10.1016/j.chom.2008.10.004 ID - Zhou2008 ER - TY - JOUR AU - Brass, A. L. AU - Dykxhoorn, D. M. AU - Benita, Y. AU - Yan, N. AU - Engelman, A. AU - Xavier, R. J. AU - Lieberman, J. AU - Elledge, S. J. PY - 2008 DA - 2008// TI - Identification of host proteins required for HIV infection through a functional genomic screen JO - Science VL - 319 UR - https://doi.org/10.1126/science.1152725 DO - 10.1126/science.1152725 ID - Brass2008 ER - TY - JOUR AU - Baldari, C. T. AU - Rosenbaum, J. PY - 2010 DA - 2010// TI - Intraflagellar transport: it’s not just for cilia anymore JO - Curr Opin Cell Biol VL - 22 UR - https://doi.org/10.1016/j.ceb.2009.10.010 DO - 10.1016/j.ceb.2009.10.010 ID - Baldari2010 ER - TY - JOUR AU - Griffiths, G. M. AU - Tsun, A. AU - Stinchcombe, J. C. PY - 2010 DA - 2010// TI - The immunological synapse: a focal point for endocytosis and exocytosis JO - J Cell Biol VL - 189 UR - https://doi.org/10.1083/jcb.201002027 DO - 10.1083/jcb.201002027 ID - Griffiths2010 ER - TY - JOUR AU - Zuo, X. AU - Guo, W. AU - Lipschutz, J. H. PY - 2009 DA - 2009// TI - The Exocyst Protein Sec10 Is Necessary for Primary Ciliogenesis and Cystogenesis In Vitro JO - Mol Biol Cell VL - 20 UR - https://doi.org/10.1091/mbc.E08-07-0772 DO - 10.1091/mbc.E08-07-0772 ID - Zuo2009 ER - TY - JOUR AU - Théry, C. AU - Ostrowski, M. AU - Segura, E. PY - 2009 DA - 2009// TI - Membrane vesicles as conveyors of immune responses JO - Nat Rev Immunol VL - 9 UR - https://doi.org/10.1038/nri2567 DO - 10.1038/nri2567 ID - Théry2009 ER - TY - JOUR AU - Gousset, K. AU - Zurzolo, C. PY - 2009 DA - 2009// TI - Tunnelling nanotubes: a highway for prion spreading? JO - Prion VL - 3 UR - https://doi.org/10.4161/pri.3.2.8917 DO - 10.4161/pri.3.2.8917 ID - Gousset2009 ER - TY - JOUR AU - Sattentau, Q. PY - 2008 DA - 2008// TI - Avoiding the void: cell-to-cell spread of human viruses JO - Nat Rev Microbiol VL - 6 UR - https://doi.org/10.1038/nrmicro1972 DO - 10.1038/nrmicro1972 ID - Sattentau2008 ER - TY - JOUR AU - Wilson, A. A. AU - Kwok, L. W. AU - Hovav, A. H. AU - Ohle, S. J. AU - Little, F. F. AU - Fine, A. AU - Kotton, D. N. PY - 2008 DA - 2008// TI - Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells JO - Am J Respir Cell Mol Biol VL - 39 UR - https://doi.org/10.1165/rcmb.2007-0133OC DO - 10.1165/rcmb.2007-0133OC ID - Wilson2008 ER - TY - JOUR AU - Zufferey, R. AU - Nagy, D. AU - Mandel, R. J. AU - Naldini, L. AU - Trono, D. PY - 1997 DA - 1997// TI - Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo JO - Nat Biotechnol VL - 15 UR - https://doi.org/10.1038/nbt0997-871 DO - 10.1038/nbt0997-871 ID - Zufferey1997 ER - TY - JOUR AU - Rho, H. M. AU - Poiesz, B. AU - Ruscetti, F. W. AU - Gallo, R. C. PY - 1981 DA - 1981// TI - Characterization of the reverse transcriptase from a new retrovirus (HTLV) produced by a human cutaneous T-cell lymphoma cell line JO - Virology VL - 112 UR - https://doi.org/10.1016/0042-6822(81)90642-5 DO - 10.1016/0042-6822(81)90642-5 ID - Rho1981 ER - TY - JOUR AU - Konig, R. AU - Zhou, Y. AU - Elleder, D. AU - Diamond, T. L. AU - Bonamy, G. M. AU - Irelan, J. T. AU - Chiang, C. Y. AU - Tu, B. P. AU - De Jesus, P. D. AU - Lilley, C. E. PY - 2008 DA - 2008// TI - Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication JO - Cell VL - 135 UR - https://doi.org/10.1016/j.cell.2008.07.032 DO - 10.1016/j.cell.2008.07.032 ID - Konig2008 ER - TY - JOUR AU - Yeung, M. L. AU - Houzet, L. AU - Yedavalli, V. S. AU - Jeang, K. T. PY - 2009 DA - 2009// TI - A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.010033 DO - 10.1074/jbc.M109.010033 ID - Yeung2009 ER - TY - STD TI - VENNY: An interactive tool for comparing lists with Venn Diagrams. , [http://bioinfogp.cnb.csic.es/tools/venny/index.html] UR - http://bioinfogp.cnb.csic.es/tools/venny/index.html ID - ref94 ER -