Figure 9

Infection of human and macaque cells with macaque- and human-derived SIV. (A) SIVagm and SIVmac produced from HSC-F cells in the absence or presence of CsA were used to infect CsA-untreated or CsA-treated target CEM-SS cells. Relative viral cDNA levels are shown as the ratio (%) of the viral cDNA levels to that of viruses produced from CsA-untreated HSC-F in CsA-untreated CEM-SS cells. Mean values and standard deviations in three independent experiments are shown. (B) SIVagm and SIVmac produced from CEM-SS cells in the absence or presence of CsA were used to infect CsA-untreated or CsA-treated target HSC-F cells. Relative viral cDNA levels are shown as the ratio (%) of the viral cDNA levels to that of viruses produced from CsA-untreated CEM-SS in CsA-untreated HSC-F cells. The relative viral cDNA levels synthesized were measured by real-time PCR. Mean values and standard deviations in three independent experiments are shown.