Figure 2
From: Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses
HTLV 1 and 2 virus-host Y2H PPI network. Big diamonds: viral ORFs, with HTLV-1 and HTLV-2 in blue and light blue, respectively. Small circles: Human ORFs, thin links: Y2H interactions; thick links: MAPPIT confirmed interactions. Human ORFs are colored according to transactivation assay results: green - down-regulation, red - up-regulation, dark red - stronger up-regulation, light green - weaker down-regulation.