Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue

Table 1 Characteristics of HIV-1+ subjects studied

Patient No.	Collection Year	Brain Bank	Disease status	CD4 count	Viral Load*	Therapy history
7766	1999	NNTC	AIDS, HAD, HIVE	43	1,843	3TC, ABC, EFV, D4T, DDI, IDV, NFV, ZDV
6568	2001	NNTC	AIDS, HAD, HIVE	77	> 750,000	3TC, ABC, D4T, DDC, DDI, EFV, IDV, NFV, NVP, ZDV
CA110	1999	UCSD	AIDS, HAD, HIVE	21	198,957	No use reported
10017	1999	Mt. Sinai	AIDS, HIVE, IVDU	7	389,120	3TC, D4T, SQV, ZDV
NA20	1993	Edinburgh	Hemophiliac**	4	--	No use reported

*Last available record prior to death
**Mild cognitive impairment, sparse giant cell encephalitis, cerebral toxoplasmosis. Status = hemophiliac

ISSN: 1742-4690