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Figure 3 | Retrovirology

Figure 3

From: Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue

Figure 3

Overall positive charge of HIV-1 V1-V2 and V1-V5 regions of envelopes amplified from brain and immune tissue. Immune tissue envelopes from four of five subjects carry a significantly higher positive charge compared to corresponding envelopes from brain. A-B: Overall positive charge of V1-V5 (A) and V1-V2 (B) amino acid sequences. All amplified envelopes shown in Figure 1 were included in this analysis.

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