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Table 2 HIV-1 integration events in control and ankyrin-expressing SupT1 cells (a)

From: Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein

Sequence

amplified

No ankyrin

Myr+AnkGAG1D4

Myr0AnkGAG1D4

Myr+AnkA32D3

Alu-gag junctions

28.3 ± 0.2

28.6 ± 0.3

30.5 ± 0.1

27.8 ± 0.2

GAPDH

25.7 ± 0.4

26.1 ± 0.5

25.5 ± 0.5

24.5 ± 0.1

  1. (a) The level of HIV-1 integration in SupT1 cells harvested at day 11 pi was evaluated by quantitative PCR amplification of host cell DNA extracts, using primers specific to Alu-gag junctions, and to cellular GAPDH gene used as the internal control. Figures shown in the Table are Cts values, mean ± SD (n = 3).
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Retrovirology

ISSN: 1742-4690

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