Figure 7
From: HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency
HERV-H expression accounts for nearly all HERV expression in human ES cells and is a not a non-specific consequence of wide-spread hypo-methylation in these cells. Quantitation of the RNA-seq reads from H1 ES cells, broken down according to the LINES, SINES, all HERVs, the nearly 1,000 HERV-H proviruses, and conventional genes. HERV-H RNA accounted for nearly all the HERV RNA in human ES cells, and 2% of total RNA. Specific vs. non-specific expression was determined by comparing the expression level of each element to the surrounding sequences.