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Figure 7 | Retrovirology

Figure 7

From: HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency

Figure 7

HERV-H expression accounts for nearly all HERV expression in human ES cells and is a not a non-specific consequence of wide-spread hypo-methylation in these cells. Quantitation of the RNA-seq reads from H1 ES cells, broken down according to the LINES, SINES, all HERVs, the nearly 1,000 HERV-H proviruses, and conventional genes. HERV-H RNA accounted for nearly all the HERV RNA in human ES cells, and 2% of total RNA. Specific vs. non-specific expression was determined by comparing the expression level of each element to the surrounding sequences.

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