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Figure 2 | Retrovirology

Figure 2

From: Systemic inhibition of myeloid dendritic cells by circulating HLA class I molecules in HIV-1 infection

Figure 2

Soluble HLA class I molecules inhibit antigen-presenting properties of MDDC. (A-B): Soluble HLA class I molecules block allostimulatory activities of MDDC. MDDC were stimulated with plasma from HIV-1 progressors, elite controllers or HIV-1 negative persons with or without prior depletion of soluble HLA class I molecules. Subsequently, MDDC were mixed with allogeneic T cells. Data reflect proportions of proliferative allogeneic T cells (A) and correlations between proliferative allogeneic T cell responses and corresponding quantities of soluble HLA class I isoforms in the plasma (B).

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Retrovirology

ISSN: 1742-4690

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