Figure 6From: A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domainsInhibition of 2DLT on HIV-1 infection. The infectivity of IIIB (subtype B, X4) in MT-2 cells (A) or HIV-1 Bal (subtype B, R5) in TZM-bl cells (B) in the presence or absence of the fusion protein (D1D2 or 2DLT) or peptide (T20 or T1144) was detected by using in-house p24 kits or Promega’s luciferase kits, respectively.Back to article page